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Sirna Therapeutics

Sirna Therapeutics (RNAI)

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Closed March 28 04:00PM
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RNAI Latest News

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PeriodChangeChange %OpenHighLowAvg. Daily VolVWAP
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RNAI Discussion

View Posts
docrew0 docrew0 17 years ago
Well that's a nice end to this story and I sold my shares in after hours. For those of you that wait this out you'll get $13 a share maybe more when the short covering begins. Good luck all.


Resumption ID
Halt
Date Halt
Time Issue
Symbol Issue Name Mkt Reason
Code Date Quote
Time Trade
Time
10/30/2006 16:38:30 RNAI Sirna Therapeutics Inc N T3 10/30/2006 17:05:00 17:10:00



4:35PM Sirna Therapeutics: Merck to acquire Sirna Therapeutics for $13/share (RNAI) 6.45 -0.04 : Merck (MRK) and RNAI announce that they have entered into a definitive agreement under which MRK will acquire RNAI. Under the terms of the agreement, MRK will acquire through a merger 100% of the equity of RNAI at a price of $13 per share in cash, making RNAI a wholly owned subsidiary of MRK. The transaction has a cash value of approximately $1.1 bln.

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docrew0 docrew0 17 years ago
New patent awarded September 19, 2006

7,109,165 Conjugates and compositions for cellular delivery
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biobio biobio 18 years ago
best to check it out yourself, but was chock full of advances and good news on many fronts..they have such a great spread of targets..and of course success in one just raises the the viability of the others..there was a not subtle hints of another deal with "major pharm" this year and new patents in US very shortly.
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ronpopeil ronpopeil 18 years ago
what did RNAI say? didn't hear the conference. thanks!
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biobio biobio 18 years ago
Check out the webcast from healthcare conference..looks like plenty of news coming in 2006 to move pps...plus i believe it will be very tightly held the next few years..OBV is extremely high with relation to float. Once over 5.50 it will start getting even more interesting.
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docrew0 docrew0 18 years ago
smd1234,

Nice to see a familiar face, welcome to the board. Your posts will be welcome here. I'm not expecting you to make a commitment. In fact I don't know how much time I'll invest here either but I do have a stake in this and these guys needed a forum that wasn't noisy.

Sorry if you’ve taken a beating in biotech’s. If you ask me Targeted Genetics being one of the first companies on the block has laid much the groundwork for sound delivery methods. I just think the street got tiered of waiting, TGEN’s day will come.

Targeted Genetics has very powerful technology don’t get me wrong but different. In fact I think it’s appropriate to mention TGEN on this board as a supporting technology. "recombinant adeno-associated virus technique for the manipulation of DNA." From Sirna’s standpoint it’s like comparing a car to its occupant. Sirna’s compounds will likely be coupled with TGEN’s AAV technology. "AAV is a naturally occurring virus that is not associated with any disease in humans. The vector efficiently delivers genetic information to numerous cell types and can be engineered to carry a variety of DNA sequences." I know TGEN is building the complete package car and occupant but Sirna is specializing in just the occupant. . . . Partner Allergan is also working on delivery methods; I’m not sure on the approach off hand.

As far as the average investor is concerned I think the PBS Nova link for RANi will sum the picture up better than me. It also delves into treating age-related macular degeneration AMD.

We should mention Targeted Genetics is partnered with Sirna Therapeutics, Inc. in the pursuit of Huntington's Disease.

All I can say is sit back and watch if you’ve been burned. I'm not going to give you a hard sell or tell you to buy. Since you and I started talking about Sirna its made better than a 10% increase. Many investors would be tickled to see that. I've kept a core position and traded my play money on the cycles. Just keep an eye on this technology that’s all I’m saying, you posed the question and this stock was ripe for a move when you asked.

In my eyes I see "Sirna" in a pure IP business model but without the legal roadblocks you and I have seen in a unrelated company.

parakeet_luck on Yahoo Msg: 21883 summed up the business side pretty good.
http://finance.messages.yahoo.com/bbs?.mm=FN&action=m&board=7077237&tid=rzym&sid=707...
- Sirna develops optimized siRNA lead compounds
- Allergan conducts and funds all pre-clinical development, clinical, regulatory, and commercialization activities
- Allergan provides proprietary and novel delivery technologies"

Currently partners like Allergan are going to drive the Sirna business plan. They will work on the delivery methods and marketing and such, Sirna will develop and patent optimized siRNA lead compounds. http://www.sfgate.com/cgi-bin/article.cgi?f=/c/a/2005/09/30/BUG7IF01SP1.DTL




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smd1234 smd1234 18 years ago
docrew0 - I have mostly lost $ in biotech, including a partner of Sirna Therapeutics called Targeted Genetics. The TGEN saga proves the impotance of paying attention - is the company really making progress, or just attracting what amounts to venture capital from wealthy partners.

I am good at DD once an idea comes to my attention, so I'll do my best for the board as time allows.

regards,

smd
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docrew0 docrew0 18 years ago
biobio,

Welcome to the RNA iHub board. You price range is historically possible and I've experienced those gap ups to be sure. Good luck

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biobio biobio 18 years ago
Greetings to you docrew0 and thank you for creating the board..2006 looks to be very interesting in the field.
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biobio biobio 18 years ago
Looking for a gap up on monday with very minimal pullback before heading back to the 5-6 dollar range..then should test 2 year high next quarter.
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docrew0 docrew0 18 years ago
Greetings,

If your reading this we can assume your interest in RNAI has been peaked. I was getting many OT questions on our other iHub board so we now have this open forum for any discussion. I’d recommend watching the PBS Nova overview as a basic primer first.

Have fun guys and let's keep it clean.

15 min PBS Nova overview
http://www.pbs.org/wgbh/nova/sciencenow/3210/02.html

Blindness
http://www.blindness.org/research.asp?id=258

Hepatitis
http://www.biospace.com/news_story.aspx?StoryID=20693220

Partnerships
http://www.sfgate.com/cgi-bin/article.cgi?f=/c/a/2005/09/30/BUG7IF01SP1.DTL

Chart
http://stockcharts.com/gallery/?RNAI

Insider Trading
http://www.secform4.com/insider/showhistory.php?symbol=rnai

Latest SEC Filings
http://www.sec.gov/cgi-bin/browse-edgar?company=&CIK=RNAI&filenum=&State=&SIC=&o....

Company news
http://phx.corporate-ir.net/phoenix.zhtml?c=141787&p=irol-news

Related developments
http://www.genome.gov/17015412


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