FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Moore Christine M
2. Issuer Name and Ticker or Trading Symbol

COMERICA INC /NEW/ [ CMA ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
EVP and General Auditor
(Last)          (First)          (Middle)

COMERICA INCORPORATED, 411 WEST LAFAYETTE, MC 3387
3. Date of Earliest Transaction (MM/DD/YYYY)

10/15/2021
(Street)

DETROIT, MI 48226
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 10/15/2021  A  1325 (1)A$0 19564 (2)D  

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Employee Stock Option (right to buy) $33.79           1/22/2014 (3)1/22/2023 Common Stock 2750.0  2750 D  
Employee Stock Option (right to buy) $49.51           1/21/2015 (3)1/21/2024 Common Stock 2205.0  2205 D  
Employee Stock Option (right to buy) $42.32           1/27/2016 (3)1/27/2025 Common Stock 2545.0  2545 D  
Employee Stock Option (right to buy) $32.97           1/26/2017 (3)1/26/2026 Common Stock 1845.0  1845 D  
Employee Stock Option (right to buy) $67.66           1/24/2018 (3)1/24/2027 Common Stock 1010.0  1010 D  
Employee Stock Option (right to buy) $95.25           1/23/2019 (3)1/23/2028 Common Stock 785.0  785 D  
Employee Stock Option (right to buy) $80.17           1/22/2020 (3)1/22/2029 Common Stock 1130.0  1130 D  
Employee Stock Option (right to buy) $63.15           1/28/2021 (3)1/28/2030 Common Stock 2150.0  2150 D  
Employee Stock Option (right to buy) $60.12           1/26/2022 (3)1/26/2031 Common Stock 1855.0  1855 D  

Explanation of Responses:
(1) Restricted stock units awarded under Issuer's Long-Term Incentive Plan.
(2) Includes shares acquired through employee stock plans, shares purchased with reinvested dividends, restricted stock units and stock units held pursuant to a deferred compensation plan as of October 15, 2021.
(3) The options vest in four equal annual installments (based on the original grant amount) beginning on the date indicated in this column.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Moore Christine M
COMERICA INCORPORATED
411 WEST LAFAYETTE, MC 3387
DETROIT, MI 48226


EVP and General Auditor

Signatures
/s/ Jennifer S. Perry, on behalf of Christine M. Moore through Power of Attorney10/19/2021
**Signature of Reporting PersonDate

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