FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

WEBER JAMES HARRY
2. Issuer Name and Ticker or Trading Symbol

COMERICA INC /NEW/ [ CMA ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
Executive Vice President
(Last)          (First)          (Middle)

1717 MAIN STREET, MC 6503
3. Date of Earliest Transaction (MM/DD/YYYY)

10/15/2021
(Street)

DALLAS, TX 75201
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 10/15/2021  A  1325 (1)A$0 16591 (2)D  

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Employee Stock Option (right to buy) $49.51           1/21/2015 (3)1/21/2024 Common Stock 1257.0  1257 D  
Employee Stock Option (right to buy) $42.32           1/27/2016 (3)1/27/2025 Common Stock 547.0  547 D  
Employee Stock Option (right to buy) $32.97           1/26/2017 (3)1/26/2026 Common Stock 650.0  650 D  
Employee Stock Option (right to buy) $67.66           1/24/2018 (3)1/24/2027 Common Stock 1335.0  1335 D  
Employee Stock Option (right to buy) $95.25           1/23/2019 (3)1/23/2028 Common Stock 995.0  995 D  
Employee Stock Option (right to buy) $80.17           1/22/2020 (3)1/22/2029 Common Stock 1375.0  1375 D  
Employee Stock Option (right to buy) $63.15           1/28/2021 (3)1/28/2030 Common Stock 2475.0  2475 D  
Employee Stock Option (right to buy) $60.12           1/26/2022 (3)1/26/2031 Common Stock 2130.0  2130 D  

Explanation of Responses:
(1) Restricted stock units awarded under Issuer's Long-Term Incentive Plan.
(2) Includes shares acquired through employee stock plans and restricted stock units as of October 15, 2021.
(3) The options vest in four equal annual installments (based on the original grant amount) beginning on the date indicated in this column.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
WEBER JAMES HARRY
1717 MAIN STREET
MC 6503
DALLAS, TX 75201


Executive Vice President

Signatures
s/ Jennifer S. Perry, on behalf of James H. Weber through Power of Attorney10/19/2021
**Signature of Reporting PersonDate

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