SFNC Simmons First National Corporation

Simmons First National Corporation (Nasdaq:SFNC) today announced it expects to release second quarter 2010 earnings prior to the market opening on Thursday, July 22, 2010, followed by a live conference call to review this information beginning at 3:00 p.m. Central Time. Interested persons can listen to this call by dialing 1-800-854-4175 (United States and Canada only) and asking for the Simmons First National Corporation conference call. A replay of the call will be available through 5:00 p.m. Central Time on July 29, 2010, by dialing 1-800-642-1687. The passcode for the replay is 84971659. In addition, the call will be available live or in recorded version on the Company's website at www.simmonsfirst.com.

Simmons First National Corporation is a financial holding company with eight community banks in Pine Bluff, Lake Village, Jonesboro, Rogers, Searcy, Russellville, El Dorado, and Hot Springs, Arkansas.  The Company's eight banks conduct financial operations from 80 offices, of which 76 are financial centers, in 41 communities.

The Simmons First National Corporation logo is available at http://www.globenewswire.com/newsroom/prs/?pkgid=4819

CONTACT:  Simmons First National Corporation
          David W. Garner, Senior Vice President and 
           Investor Relations Officer
          (870) 541-1000