FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Garner David W
2. Issuer Name and Ticker or Trading Symbol

SIMMONS FIRST NATIONAL CORP [ SFNC ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
EVP, Chief Accounting Officer
(Last)          (First)          (Middle)

SIMMONS FIRST NATIONAL CORPORATION, 501 MAIN STREET
3. Date of Earliest Transaction (MM/DD/YYYY)

1/24/2022
(Street)

PINE BLUFF, AR 71601
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 1/24/2022  M  3520 A$29.70 53850 (2)D  
Common Stock 1/24/2022  F  1238 D$29.70 52612 D  
Common Stock         6000 I By Trust (Mother) 

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Performance Stock Unit $29.70 1/24/2022  M     3520   (1) (1)Common 3520 $0 0 D  

Explanation of Responses:
(1) The Performance Stock Units were subject to certain performance-based vesting requirements, attainment of which was certified by the Company's Compensation Committee on January 24, 2022. The Performance Stock Units vested on January 24, 2022. Shares will be delivered within 30 days of vesting
(2) Includes 819 shares acquired by the Reporting Person pursuant to the Issuer's Employee Stock Purchase Plan.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Garner David W
SIMMONS FIRST NATIONAL CORPORATION
501 MAIN STREET
PINE BLUFF, AR 71601


EVP, Chief Accounting Officer

Signatures
/s/ David W. Garner by Natalie Gassiott1/26/2022
**Signature of Reporting PersonDate

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