By Rex Crum, MarketWatch

SAN FRANCISCO (MarketWatch) -- Gains from Adobe Systems Inc. stood out in the tech sector Friday, but losses from Apple Inc. and others kept tech stocks from launching any meaningful rally to end the week.

Apple (AAPL) shares fell almost 4%, to close at $509.79. Before the start of trading, UBS analyst Steven Milunovich cut his price target on Apple's stock to $700 a share from $780.

In a research note, Milunovich said he was taking a slightly more conservative view on Apple due to supply chain checks that suggest a decline in iPhone production in the March quarter of 2013, and that the new iPad Mini could be cannibalizing some sales of the iPad.

With Apple's losses leading the way, the Nasdaq Composite Index (RIXF) fell more than 20 points, to close at 2.971. The Philadelphia Semiconductor Index (SOX) and the Morgan Stanley High Tech 35 Index also ended the day with losses.

VeriFone Systems Inc. (PAY) was another big decliner, falling almost 11%, to close at $29.60 after the payment-processing technology company reported a wider quarterly loss late Thursday.

Losses also came from Dell Inc. (DELL), Microsoft Corp. (MSFT), Seagate Technology (STX) and Qualcomm Inc. (QCOM).

Adobe (ADBE) shares rose almost 6%, to close at $37.56 after the software company reported better-than-expected quarterly earnings after the close of trading on Thursday. Adobe earned 61 cents a share, excluding one-time items, on $1.15 billion in revenue, while analysts has forecast the company to earn 57 cents a share, on sales of $1.1 billion.

Groupon Inc. (GRPN) shares rose almost 3%, to end the day at $4.93, after earlier rising above $5 a share for the first time since Oct. 18.

Other gainers included Oracle Corp. (ORCL), IBM Corp. (IBM), Yahoo Inc. (YHOO) and Nvidia Corp. (NVDA).

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