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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
Form 8-K
Current Report
Pursuant to Section 13 or 15(d) of the
Securities Exchange Act of 1934
March 24, 2024
Date of Report (Date of earliest event reported)
Zura
Bio Limited
(Exact Name of Registrant
as Specified in its Charter)
Cayman Islands |
|
001-40598 |
|
98-1725736 |
(State or other jurisdiction
of incorporation) |
|
(Commission
File Number) |
|
(I.R.S. Employer
Identification No.) |
1489 W. Warm Springs Rd. #110 |
|
|
Henderson, Nevada |
|
89014 |
(Address of Principal Executive Offices) |
|
(Zip Code) |
Registrant's telephone number,
including area code: (702) 757-6133
N/A
(Former name or former address,
if changed since last report)
Check the appropriate box below if the Form 8-K
filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
¨ | Written communication pursuant to Rule 425 under the Securities Act
(17 CFR 230.425) |
¨ | Soliciting material pursuant to Rule 14a-12 under the Exchange Act
(17 CFR 240.14a-12) |
¨ | Pre-commencement communications pursuant to Rule 14d-2(b) under the
Exchange Act (17 CFR 240.14d-2(b)) |
¨ | Pre-commencement communications pursuant to Rule 13e-4(c) under the
Exchange Act (17 CFR 240.13e-4(c)) |
Securities registered pursuant to Section 12(b) of the Act:
Title of each class |
|
Trading
Symbol(s) |
|
Name
of each exchange on
which registered |
Class A Ordinary Shares, par value $0.0001 per share |
|
ZURA |
|
The Nasdaq Stock Market |
Warrants, each whole warrant exercisable for one Class A Ordinary Share at an exercise price of $11.50 per share |
|
ZURAW |
|
The Nasdaq Stock Market |
Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (17 CFR §230.405) or Rule 12b-2 of the Securities Exchange Act of 1934 (17 CFR §240.12b-2).
Emerging growth company x
If an emerging growth company, indicate by check mark if the registrant
has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant
to Section 13(a) of the Exchange Act.
Item 2.02 Results of Operations and Financial
Condition.
On
March 28, 2024, Zura Bio Limited (“ZURA”, the “Company”) issued a press release
announcing its 2023 full fiscal year financial results. A copy of the press release is furnished herewith as Exhibit 99.1 and incorporated
herein by reference.
The information in this
Item 2.02 shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, nor shall it be deemed
incorporated by reference in any Company filing under the Securities Act of 1933 or the Securities Exchange Act of 1934, except as shall
be expressly set forth by specific reference in such filing.
Item 5.02 Departure of Directors or Certain
Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.
Transition of Chief Executive Officer.
On March 24, 2024, the board of directors of ZURA (the “Board”)
approved a Chief Executive Officer (“CEO”) transition from Someit Sidhu, our Founder, CEO and Director, to Robert
Lisicki, effective April 8, 2024. Dr. Sidhu joined ZURA as the founding CEO at the time ZURA became a public company. Dr. Sidhu led the
in-licensing of the Company’s current pipeline molecules including tibulizumab, a bispecific antibody which is a dual antagonist
of BAFF and IL-17. In addition, Dr. Sidhu completed a successful capital raise enabling the Company to meaningfully advance the development
of its assets.
Mr. Lisicki, the Company’s
current President and Chief Operating Officer, will be promoted to the Company’s Chief Executive Officer on April 8, 2024. Dr. Sidhu
will remain on the Board as a non-independent Director and Mr. Lisicki will join the Board as a non-independent Director increasing its
membership from nine Directors to ten.
Except as otherwise set forth
herein, there is no arrangement or understanding between Mr. Lisicki and any other person pursuant to which he was appointed as the Chief
Executive Officer, and there are no transactions in which Mr. Lisicki has an interest requiring disclosure under Item 404(a) of Regulation
S-K. In connection with the appointment, the Company expects to enter into its standard indemnification agreement with Mr. Lisicki, on
substantially the same terms as the indemnification agreements previously entered into between the Company and each of its directors and
executive officers.
Item 9.01 Financial Statements and Exhibits.
(d) Exhibits:
SIGNATURES
Pursuant to the requirements of the Securities
Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
Dated: March 28, 2024 |
|
|
|
ZURA BIO LIMITED |
|
|
|
By: |
/s/ Kim Davis |
|
Name: |
Kim Davis |
|
Title: |
Chief Legal Officer |
|
Exhibit 99.1
Zura Bio Reports Full Year 2023 Financial Results,
Business
Highlights, and Appoints Robert Lisicki as Chief Executive Officer
- | Significant 2023 milestones highlighted by successful Nasdaq listing, leadership team buildout, formation
of strategic development and scientific plan |
| |
- | On track to initiate Phase 2 study evaluating tibulizumab (ZB-106) for the treatment of systemic sclerosis
(SSc) in 2H 2024 |
| |
- | Appointment of CEO, Robert Lisicki, underscores Zura Bio’s commitment to building leading immunology
company as we prioritize excellence in strategic development and scientific planning |
| |
- | Outgoing Founder and CEO, Someit Sidhu, M.D., will continue as a Board Director to leverage institutional
knowledge and provide continued support |
| |
| - | Cash position as of December 31, 2023 totaling $99.8 million in cash, cash equivalents, and investments
expected to support development and operations into 2026 |
Henderson, Nev – March 28, 2024 - Zura
Bio Limited (Nasdaq: ZURA) (“Zura Bio”) a clinical-stage immunology company developing novel dual-pathway antibodies
for autoimmune and inflammatory diseases, today reported full year 2023 financial results and recent business highlights. The Company
has also announced the appointment of Robert Lisicki as Chief Executive Officer (CEO), effective April 8, 2024, succeeding its Founding
CEO, Someit Sidhu, M.D. Dr. Sidhu will continue to serve Zura Bio as a non-independent Board Director.
“Throughout 2023, Zura Bio achieved significant
milestones by successfully listing on Nasdaq, broadening our portfolio of differentiated clinical-stage immunology and inflammation assets,
and building our management team. These accomplishments have firmly established a robust operational framework for our business that is
underpinned by a cash runway expected to fund operations into 2026,” stated Someit Sidhu, M.D., Founder and CEO of Zura Bio, “We
remain focused on initiating a Phase 2 clinical trial evaluating our lead asset, tibulizumab, in systemic sclerosis in the second half
of 2024. This involves effective management of our development and manufacturing partners, the thoughtful selection of a contract research
organization, and communications with regulatory authorities. Concurrently, we're advancing ZB-168 and torudokimab towards Phase 2 readiness
while closely monitoring external readouts expected in 2024.”
Zura Bio has appointed Robert Lisicki as CEO,
effective April 8, 2024, succeeding Dr. Sidhu, who remains actively involved in the Company as a non-independent Director of
the Board. The Company will expand its Board membership to ten, which includes Mr. Lisicki’s role as a Director of the Board.
Mr. Lisicki joined Zura Bio in January 2024 as President and Chief Operating Officer.
Dr. Sidhu continued, "On behalf of the
Management Team and Board, I am pleased to welcome Robert as the Chief Executive Officer. Robert brings a wealth of industry leadership
experience complemented by expertise in drug development and commercial operations. With his proven track record of excellence, he is
the right individual to lead Zura Bio as our lead asset enters Phase 2 development. I will work closely with Robert to transition CEO
responsibilities and remain actively involved as a Director."
Important
upcoming anticipated events for Zura Bio
Tibulizumab (ZB-106): Zura Bio plans
to initiate a Phase 2 trial of tibulizumab for the treatment of systemic sclerosis in 2H 2024. Tibulizumab is a tetravalent dual-antagonist
antibody engineered by the fusion of TALTZ® (ixekizumab) and tabalumab that neutralizes IL-17A and BAFF.
ZB-168: Zura Bio plans to conduct
necessary CMC and regulatory activities to prepare ZB-168, an anti-IL-7Rα inhibitor, for Phase 2 readiness. Additionally, the Company
is actively monitoring Phase 2 IL-7R external catalysts in ulcerative colitis, atopic dermatitis, and alopecia areata, along with additional
TSLP-driven catalysts.
Torudokimab (ZB-880): Zura Bio plans
to conduct necessary CMC and regulatory activities to prepare torudokimab, an anti-IL-33 antibody, for Phase 2 readiness in allergy or
respiratory-related indications. Additionally, the Company is monitoring Phase 2 and Phase 3 external catalysts in asthma and chronic
obstructive pulmonary disease.
BUSINESS AND FINANCIAL HIGHLIGHTS
| • | Raised approximately $145 million in 1H 2023
to support our pipeline and business operations. |
| o | In March 2023, successfully closed a Business Combination Agreement (BCA) with JATT Acquisition Corp.,
resulting in approximately $65 million in gross cash proceeds. Simultaneously, began trading on Nasdaq under the ticker symbol ZURA. |
| o | In April 2023, completed $80 million financing from top institutional biotech investors supporting
the in-licensing of tibulizumab, a potential first-in-class anti-IL-17 and anti-BAFF tetravalent bispecific antibody, from Eli Lilly and
Company. |
| • | Enhanced and expanded
the Board of Directors and Executive leadership team to fortify business operations and ensure readiness for clinical trials in 2024. |
| o | In April 2023, appointed Michael Howell, Ph.D. as the Chief Scientific Officer and Head of Translational
Medicine. |
| o | In November 2023, appointed Arnout Ploos van Amstel to the Board of Directors. |
| o | In January 2024, appointed Kiran Nistala, M.B.B.S., Ph.D. as the Chief Medical Officer and Head of
Development. |
| o | In March 2024, appointed Robert Lisicki to CEO, effective April 8, 2024. |
| • | Joined the Russell 2000® and Russell 3000®
Indexes in June 2023. |
| • | Entered into a sponsored research agreement with
Benaroya Research Institute in September 2023 to further characterize the pivotal role of Interleukin-7 receptor alpha (IL-7Rα)
in Thymic Stromal Lymphopoietin (TSLP) and Interleukin-7 (IL-7) signaling pathways. |
| • | Presented results from two abstracts at the World
Allergy Congress in December 2023, highlighting the Company’s informative research for ZB-168 and torudokimab. |
Cash and cash equivalents: Cash and
cash equivalents were $99.8 million as of December 31, 2023, as compared to $1.6 million as of December 31,
2022. The increased cash balance is primarily due to the aggregate of capital raised from closing of the BCA in March 2023 and the
private placement transaction in April 2023. Zura Bio anticipates that its cash and cash equivalents are sufficient to fund planned
operations into 2026.
Research and Development (R&D) expenses: R&D
expenses were $44.0 million for the year ended December 31, 2023, an increase of $20.3 million compared to $23.7 million for the
year ended December 31, 2022. The increase was primarily due to an increase of $9.1 million related to manufacturing, and an increase
of $7.5 million of costs incurred to acquire licenses. Additionally, there was an increase of $1.5 million in expenses related to compensation
for personnel, including share-based compensation.
General and Administrative (G&A) expenses:
G&A expenses were $18.6 million for the year ended December 31, 2023, an increase of $15.2 million compared to the $3.5 million
for the year ended December 31, 2022. The increase was primarily due to an increase of $11.4 million in compensation for personnel
in G&A functions, including share-based compensation as well as an increase of $2.9 million in professional services.
Net loss: Net loss for the year ended December 31,
2023 was $60.4 million compared to $25.7 million for the year ended December 31, 2022.
ABOUT ZURA BIO
Zura Bio is a clinical-stage, multi-asset immunology
company developing novel dual-pathway antibodies for autoimmune and inflammatory diseases. Currently, Zura Bio is developing three assets
which have completed Phase 1/1b studies and are Phase 2 ready. The company is developing a portfolio of therapeutic indications for tibulizumab,
ZB-168, and torudokimab with a goal of demonstrating their efficacy, safety, and dosing convenience in autoimmune and inflammatory diseases,
including systemic sclerosis and other novel indications with unmet needs.
Forward-Looking
Statements
This communication includes “forward-looking
statements” within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995.
Words such as “expect,” “estimate,” “project,” “budget,” “forecast,” “anticipate,”
“intend,” “plan,” “may,” “will,” “could,” “should,” “believe,”
“predict,” “potential,” “continue,” “strategy,” “future,” “opportunity,”
“would,” “seem,” “seek,” “outlook” and similar expressions are intended to identify such
forward-looking statements. Forward-looking statements are predictions, projections and other statements about future events that are
based on current expectations and assumptions and, as a result, are subject to risks and uncertainties that could cause the actual results
to differ materially from the expected results. These statements are based on various assumptions, whether or not identified in this communication.
These forward-looking statements are provided for illustrative purposes only and are not intended to serve as, and must not be relied
on by an investor as, a guarantee, an assurance, a prediction or a definitive statement of fact or probability.
Actual events and circumstances are difficult
or impossible to predict and will differ from assumptions. You should carefully consider the risks and uncertainties described in the
“Risk Factors” sections of Zura Bio’s recent filings with the SEC. These filings would identify and address other
important risks and uncertainties that could cause actual events and results to differ materially from those contained in the forward-looking
statements. Many of these factors are outside Zura Bio’s control and are difficult to predict. Many factors could cause actual future
events to differ from the forward-looking statements in this communication, including but not limited to: (1) the outcome of any
legal proceedings that may be instituted against Zura Bio; (2) volatility in the price of Zura Bio’s securities; (3) the
ability of Zura Bio to successfully conduct research and development activities, grow and manage growth profitably, maintain relationships
with customers and suppliers, and retain key employees; (4) the ongoing costs relating to operating as a public company; (5) changes
in the applicable laws or regulations; (6) the possibility that Zura Bio may be adversely affected by other economic, business, and/or
competitive factors; (7) the risk of downturns and a changing regulatory landscape in the highly competitive industry in which Zura
Bio operates; (8) the potential inability of Zura Bio to raise additional capital needed to pursue its business objectives or to
achieve efficiencies regarding other costs; (9) the enforceability of Zura Bio’s intellectual property, including its patents,
and the potential infringement on the intellectual property rights of others, cyber security risks or potential breaches of data security;
and (10) other risks and uncertainties described in the registration statement on Form S-1 filed with the SEC on June 14,
2023, and such other documents filed by Zura Bio from time to time with the SEC. These risks and uncertainties may be amplified by
the COVID-19 pandemic or other unanticipated global disruption events, which may continue to cause economic uncertainty. Zura Bio cautions
that the foregoing list of factors is not exclusive or exhaustive and not to place undue reliance upon any forward-looking statements,
including projections, which speak only as of the date made. Zura Bio gives no assurance that it will achieve its expectations. Zura Bio
does not undertake or accept any obligation to publicly provide revisions or updates to any forward-looking statements, whether as a result
of new information, future developments or otherwise, or should circumstances change, except as otherwise required by securities and other
applicable laws.
Contacts
Megan K. Weinshank
Head of Investor Relations
IR@zurabio.com
Lee M. Stern
Meru Advisors
lstern@meruadvisors.com
ZURA BIO LIMITED
CONSOLIDATED BALANCE SHEETS
| |
December 31, | | |
December 31, | |
| |
2023 | | |
2022 | |
Assets | |
| | | |
| | |
Current assets: | |
| | | |
| | |
Cash and cash equivalents | |
$ | 99,806 | | |
$ | 1,567 | |
Prepaid expenses and other current assets | |
| 1,037 | | |
| 209 | |
Total current assets | |
| 100,843 | | |
| 1,776 | |
Deferred offering costs | |
| — | | |
| 3,486 | |
Total assets | |
$ | 100,843 | | |
$ | 5,262 | |
| |
| | | |
| | |
Liabilities, Redeemable Noncontrolling Interest, Convertible Preferred Shares, and Shareholders’ Equity (Deficit) | |
| | | |
| | |
Current liabilities: | |
| | | |
| | |
Accounts payable and accrued expenses | |
$ | 20,302 | | |
$ | 4,428 | |
Note payable | |
| — | | |
| 7,756 | |
Research and development license consideration liability | |
| — | | |
| 2,634 | |
Total current liabilities | |
| 20,302 | | |
| 14,818 | |
Private placement warrants | |
| 990 | | |
| — | |
Total liabilities | |
| 21,292 | | |
| 14,818 | |
| |
| | | |
| | |
Commitments and contingencies (Note 12) | |
| | | |
| | |
| |
| | | |
| | |
Redeemable noncontrolling interest | |
| 18,680 | | |
| 10,000 | |
| |
| | | |
| | |
Convertible preferred shares | |
| | | |
| | |
Series A-1 convertible preferred shares, $0.001 par value, -0- and 13,510,415 shares authorized, issued and outstanding as of December 31, 2023 and 2022, respectively | |
| — | | |
| 12,500 | |
| |
| | | |
| | |
Shareholders’ Equity (Deficit): | |
| | | |
| | |
Preferred Shares, $0.0001 par value, 1,000,000 and -0- authorized as of December 31, 2023 and 2022, respectively; -0- issued and outstanding as of December 31, 2023 and 2022 | |
| — | | |
| — | |
Class A Ordinary Shares, $0.0001 par value, 300,000,000 authorized, 43,593,678 issued and outstanding as of December 31, 2023; 1,884,649 authorized, 279,720 issued and outstanding as of December 31, 2022 | |
| 4 | | |
| — | |
Additional paid-in capital | |
| 162,820 | | |
| — | |
Accumulated deficit | |
| (103,494 | ) | |
| (32,056 | ) |
Total Zura Bio Limited shareholders’ equity (deficit) | |
| 59,330 | | |
| (32,056 | ) |
Noncontrolling interest | |
| 1,541 | | |
| — | |
Total shareholders’ equity (deficit) | |
| 60,871 | | |
| (32,056 | ) |
Total liabilities, redeemable noncontrolling interest, convertible preferred shares, and shareholders’ equity (deficit) | |
$ | 100,843 | | |
$ | 5,262 | |
ZURA BIO LIMITED
CONSOLIDATED STATEMENTS OF OPERATIONS
(In thousands, except share and per share data)
| |
| | |
For the Period from | |
| |
| | |
January 18, 2022 | |
| |
For the Year Ended | | |
(date of inception) to | |
| |
December 31, | | |
December 31, | |
| |
2023 | | |
2022 | |
Operating expenses: | |
| | | |
| | |
Research and development | |
$ | 43,999 | | |
$ | 23,689 | |
General and administrative | |
| 18,639 | | |
| 3,473 | |
Total operating expenses | |
| 62,638 | | |
| 27,162 | |
Loss from operations | |
| (62,638 | ) | |
| (27,162 | ) |
Other expense/(income), net: | |
| | | |
| | |
Other expense, net | |
| (17 | ) | |
| 23 | |
Interest income | |
| (2,186 | ) | |
| (8 | ) |
Dividend income | |
| (1,392 | ) | |
| — | |
Change in fair value of private placement warrants | |
| (724 | ) | |
| — | |
Change in fair value of note payable | |
| 2,244 | | |
| 156 | |
Total other expense/(income), net | |
| (2,075 | ) | |
| 171 | |
Loss before income taxes | |
| (60,563 | ) | |
| (27,333 | ) |
Income tax benefit | |
| — | | |
| — | |
Net loss before redeemable noncontrolling interest | |
| (60,563 | ) | |
| (27,333 | ) |
Net loss attributable to redeemable noncontrolling interest | |
| 203 | | |
| 1,595 | |
Net loss | |
| (60,360 | ) | |
| (25,738 | ) |
Accretion of redeemable noncontrolling interest to redemption value | |
| (7,220 | ) | |
| (6,652 | ) |
Deemed contribution from redeemable noncontrolling interest | |
| 9,212 | | |
| — | |
Deemed dividend to redeemable noncontrolling interest | |
| (10,875 | ) | |
| — | |
Net loss attributable to Class A Ordinary Shareholders of Zura | |
$ | (69,243 | ) | |
$ | (32,390 | ) |
Net loss per share attributable to Class A Ordinary Shareholders of Zura, basic and diluted | |
$ | (2.09 | ) | |
$ | (141.97 | ) |
Weighted-average Class A Ordinary Shares used in computing net loss per share attributable to Class A Ordinary Shareholders of Zura, basic and diluted | |
| 33,064,036 | | |
| 228,148 | |
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Grafico Azioni JATT Acquisition (NYSE:JATT)
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Da Mag 2024 a Giu 2024
Grafico Azioni JATT Acquisition (NYSE:JATT)
Storico
Da Giu 2023 a Giu 2024