UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G/A

Under the Securities Exchange Act of 1934
(Amendment No. 2)

Mindray Medical International Limited
(Name of Issuer)

Class A ordinary shares, par value $0.001 per share
(Title of Class of Securities)

602675100
(CUSIP Number)

December 31, 2010
(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

[ ] Rule 13d-1(b)

[X] Rule 13d-1(c)

[ ] Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).


 CUSIP No. 602675100


 1. Names of Reporting Persons.

 Joho Capital, L.L.C.

 2. Check the Appropriate Box if a Member Of a Group

 [ ] (a)
 [X] (b)

 3. SEC Use Only

 4. Citizenship or Place of Organization

 Delaware, United States

 5. Sole Voting Power: 0
Number of Shares
 6. Shared Voting Power: 1,559,666
Beneficially Owned by
 7. Sole Dispositive Power: 0
Each Reporting Person With:
 8. Shared Dispositive Power: 1,559,666

 9. Aggregate Amount Beneficially Owned by Each Reporting Person

 1,559,666

 10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares

 11. Percent of Class Represented by Amount in Row (9)

 1.85%

 12. Type of Reporting Person

 CO


 CUSIP No. 602675100


 1. Names of Reporting Persons.

 Robert Karr

 2. Check the Appropriate Box if a Member Of a Group

 [ ] (a)
 [X] (b)

 3. SEC Use Only

 4. Citizenship or Place of Organization

 United States of America

 5. Sole Voting Power: 0
Number of Shares
 6. Shared Voting Power: 1,559,666
Beneficially Owned by
 7. Sole Dispositive Power: 0
Each Reporting Person With:
 8. Shared Dispositive Power: 1,559,666

 9. Aggregate Amount Beneficially Owned by Each Reporting Person

 1,559,666

 10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares

 11. Percent of Class Represented by Amount in Row (9)

 1.85%

 12. Type of Reporting Person

 IN


Item 1. (a) Name of Issuer: Mindray Medical International Limited

(b) Address of Issuer's Principal Executive Offices:

Mindray Building, Keji 12th Road South, Hi-Tech Industrial Park, Nanshan, Shenzhen 518057
People's Republic of China

Item 2. (a) Name of Person Filing:

Joho Capital, L.L.C.
Robert Karr

(b) Address of Principal Business Office, or, if None, Residence:

55 E. 59th Street
New York, NY 10022
United States

(c) Citizenship:
Please refer to Item 4 on each cover sheet for each filing person

(d) Title of Class of Securities:
Class A ordinary shares, par value $0.001 per share

(e) CUSIP No.: 602675100

Item 3. If This Statement is Filed Pursuant to Rules 13d-1(b), or 13d-2(b) or
(c), Check Whether the Person Filing is a:

(a) [ ] Broker or dealer registered under Section 15 of the Act.

(b) [ ] Bank as defined in Section 3(a)(6) of the Act.

(c) [ ] Insurance company as defined in Section 3(a)(19) of the Act.

(d) [ ] Investment company registered under Section 8 of the Investment Company Act of 1940.

(e) [ ] An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E);

(f) [ ] An employee benefit plan or endowment fund in accordance with Rule 13d-1(b)(1)(ii)(F);

(g) [ ] A parent holding company or control person in accordance with Rule 13d-1(b)(1)(ii)(G);

(h) [ ] A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);

(i) [ ] A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940;

(j) [ ] Group, in accordance with Rule 13d-1(b)(1)(ii)(J).


Item 4. Ownership

Please see Items 5 - 9 and 11 on each cover sheet for each Reporting Person

Item 5. Ownership of Five Percent or Less of a Class

X

Item 6. Ownership of More than Five Percent on Behalf of Another Person

Not Applicable

Item 7. Identification and Classification of the Subsidiary Which Acquired
the Security Being Reported on By the Parent Holding Company or Control Person

Not Applicable

Item 8. Identification and Classification of Members of the Group

Not Applicable

Item 9. Notice of Dissolution of Group

Not Applicable


Item 10. Certifications

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.


SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Dated: February 14, 2011
Joho Capital, L.L.C.

By: /s/ Timothy K. McManus
--------------------------
Name: Timothy K. McManus
Title: Chief Financial Officer

By: /s/ Robert Karr
--------------------------
Name: Robert Karr


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