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| Data | Nome del titolare | Azioni transazionate | Intervallo di valore ($) | Tipo di transazione | Intervallo di prezzo ($) | Azioni a fine dichiarazione | % di variazione |
|---|---|---|---|---|---|---|---|
| 2026-05-18 | Dr. David M. RodmanChief Medical Officer | -417,00 | 5,05k | Derivative Exercise and Sale | 15,44 - 27,55 | 63,44k | - |
| 2026-05-13 | Dr. David M. RodmanChief Medical Officer | -6,35k | 181,49k | Automatic Disposition | 28,58 | 63,44k | -9,10% |
| 2026-05-11 | Dr. David M. RodmanChief Medical Officer | -16,23k | 334,08k | Derivative Exercise and Sale | 1,08 - 29,71 | 63,44k | - |
| 2026-04-17 | Dr. David M. RodmanChief Medical Officer | -416,00 | 6,61k | Derivative Exercise and Sale | 15,44 - 31,33 | 69,79k | - |
| 2026-04-13 | Dr. David M. RodmanChief Medical Officer | -14,06k | 270,72k | Derivative Exercise and Sale | 1,08 - 26,54 | 69,79k | - |
| 2026-04-15 | Dr. David M. RodmanChief Medical Officer | -6,35k | 175,59k | Automatic Disposition | 27,66 | 69,79k | -8,34% |
| 2026-04-13 | Mr. Jon CongletonPresident, CEO & Director | -15,73k | 421,98k | Automatic Disposition | 26,83 | 548,42k | -2,79% |
| 2026-04-09 | Dr. David M. RodmanChief Medical Officer | -2,17k | 24,69k | Derivative Exercise and Sale | 16,00 - 27,38 | 76,14k | - |
| 2026-03-31 | Mr. Jon CongletonPresident, CEO & Director | -75,00k | 1,97M | Automatic Disposition | 25,50 - 27,05 | 564,15k | -11,73% |
| 2026-03-31 | Ms. Daphne KarydasIndependent Director | -3,00k | 38,94k | Derivative Exercise and Sale | 12,02 - 25,00 | 6,20k | - |
| 2026-03-27 | RA Capital Management, L.P.Società | 369,00k | 8,76M | Acquisto | 23,67 - 24,16 | 7,69M | 5,04% |
| 2026-03-17 | Dr. David M. RodmanChief Medical Officer | -417,00 | 4,26k | Derivative Exercise and Sale | 15,44 - 25,65 | 76,14k | - |
| 2026-03-12 | Dr. David M. RodmanChief Medical Officer | -14,06k | 271,13k | Derivative Exercise and Sale | 1,08 - 27,37 | 76,14k | - |
| 2026-03-13 | Dr. David M. RodmanChief Medical Officer | -6,35k | 169,48k | Automatic Disposition | 25,91 - 27,82 | 76,14k | -7,70% |
| 2026-03-09 | Dr. David M. RodmanChief Medical Officer | -2,17k | 23,53k | Derivative Exercise and Sale | 16,00 - 26,84 | 44,09k | - |
| 2026-02-19 | Dr. Brian Taylor SlingsbyFounder & Executive Director | -6,20k | 0,00 | Other Disposition | - | 0,00 | -100,00% |
| 2026-02-19 | Dr. Brian Taylor SlingsbyFounder & Executive Director | -8,30k | 0,00 | Other Derivative Disposition | 28,06 | 0,00 | -100,00% |
| 2026-02-17 | Dr. David M. RodmanChief Medical Officer | -417,00 | 5,07k | Derivative Exercise and Sale | 15,44 - 27,59 | 44,09k | - |
| 2026-02-12 | Dr. David M. RodmanChief Medical Officer | -14,06k | 292,37k | Derivative Exercise and Sale | 1,08 - 29,64 | 44,09k | - |
| 2026-02-13 | Dr. David M. RodmanChief Medical Officer | -6,35k | 175,10k | Automatic Disposition | 27,58 | 44,09k | -12,59% |
| 2026-02-09 | Dr. David M. RodmanChief Medical Officer | -2,17k | 30,85k | Derivative Exercise and Sale | 16,00 - 30,21 | 50,44k | - |
| 2026-01-20 | Dr. David M. RodmanChief Medical Officer | -416,00 | 6,93k | Derivative Exercise and Sale | 15,44 - 32,10 | 50,44k | - |
| 2026-01-13 | Dr. David M. RodmanChief Medical Officer | -7,71k | 156,96k | Derivative Exercise and Sale | 10,20 - 32,75 | 50,44k | - |
| 2026-01-14 | Dr. David M. RodmanChief Medical Officer | -11,37k | 370,64k | Automatic Disposition | 32,61 | 50,44k | -18,39% |
| 2026-01-12 | Mr. Adam Scott LevyCFO & Secretary | -10,76k | 345,72k | Automatic Disposition | 32,14 | 8,64k | -55,47% |
| 2026-01-09 | Dr. David M. RodmanChief Medical Officer | -8,52k | 235,76k | Derivative Exercise and Sale | 1,08 - 33,27 | 61,80k | - |
| 2026-01-12 | Mr. Jon CongletonPresident, CEO & Director | -16,24k | 529,64k | Automatic Disposition | 32,21 - 33,15 | 639,15k | -2,48% |
| 2026-01-02 | Dr. David M. RodmanChief Medical Officer | -252,72k | 5,80M | Derivative Exercise and Sale | 1,08 - 35,87 | 61,80k | - |
| 2026-01-02 | Dr. David M. RodmanChief Medical Officer | -10,03k | 357,26k | Automatic Disposition | 35,53 - 35,87 | 61,80k | -13,96% |
| 2025-11-21 | Mr. Jon CongletonPresident, CEO & Director | 24,08k | 13,00k | Derivative Exercise and Retained Stock | 0,54 | 655,39k | 3,81% |
| 2025-11-20 | Catalys PacificSocietà | -1.000,00k | 43,35M | Vendita | 43,35 | 7,90M | -11,23% |
| 2025-11-11 | Mr. Jon CongletonPresident, CEO & Director | -200,00k | 9,09M | Vendita | 41,64 - 46,89 | 631,31k | -24,06% |
| 2025-11-11 | Mr. Adam Scott LevyCFO & Secretary | -105,65k | 3,22M | Derivative Exercise and Sale | 10,20 - 46,88 | 19,40k | - |
| 2025-11-11 | Mr. Adam Scott LevyCFO & Secretary | -13,87k | 650,34k | Vendita | 46,88 | 19,40k | -41,70% |
| 2025-11-11 | Dr. Alexander M. GoldIndependent Director | -34,68k | 1,20M | Derivative Exercise and Sale | 10,20 - 47,28 | 0,00 | - |
| 2025-11-13 | Ms. Daphne KarydasIndependent Director | -15,00k | 536,80k | Derivative Exercise and Sale | 10,20 - 46,36 | 0,00 | - |
| 2025-10-13 | Mr. Jon CongletonPresident, CEO & Director | -15,10k | 644,33k | Automatic Disposition | 42,63 - 43,03 | 831,31k | -1,78% |
| 2025-10-13 | Mr. Adam Scott LevyCFO & Secretary | -10,76k | 451,98k | Automatic Disposition | 41,90 - 42,26 | 116,87k | -8,43% |
| 2025-10-15 | Dr. David M. RodmanChief Medical Officer | -10,37k | 445,98k | Automatic Disposition | 43,01 | 71,16k | -12,72% |
| 2025-09-15 | Dr. David M. RodmanChief Medical Officer | -11,37k | 409,27k | Automatic Disposition | 35,90 - 36,47 | 81,52k | -12,24% |
| 2025-09-04 | RA Capital Management, L.P.Società | 1,18M | 30,00M | Acquisto | 25,50 | 7,32M | 19,14% |
| 2025-08-12 | Dr. David M. RodmanChief Medical Officer | -6,35k | 75,26k | Derivative Exercise and Sale | 1,08 - 12,93 | 92,89k | - |
| 2025-08-13 | Dr. David M. RodmanChief Medical Officer | -5,02k | 64,87k | Automatic Disposition | 12,93 | 92,89k | -5,12% |
| 2025-07-28 | Mr. Adam Scott LevyCFO & Secretary | -73,68k | 1,08M | Vendita | 14,00 - 15,10 | 132,93k | -35,66% |
| 2025-07-11 | Mr. Jon CongletonPresident, CEO & Director | -15,88k | 230,43k | Automatic Disposition | 14,51 | 846,41k | -1,84% |
| 2025-07-14 | Dr. David M. RodmanChief Medical Officer | -6,35k | 85,80k | Derivative Exercise and Sale | 1,08 - 14,59 | 97,91k | - |
| 2025-07-14 | Dr. David M. RodmanChief Medical Officer | -5,02k | 73,22k | Automatic Disposition | 14,59 | 97,91k | -4,87% |
| 2025-07-11 | Mr. Adam Scott LevyCFO & Secretary | -10,76k | 155,45k | Automatic Disposition | 14,45 | 206,61k | -4,95% |
| 2025-06-12 | Dr. David M. RodmanChief Medical Officer | -6,35k | 85,82k | Derivative Exercise and Sale | 1,08 - 14,60 | 101,65k | - |
| 2025-06-13 | Dr. David M. RodmanChief Medical Officer | -5,02k | 73,26k | Automatic Disposition | 14,60 | 101,65k | -4,70% |
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