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| Data | Nome del titolare | Azioni transazionate | Intervallo di valore ($) | Tipo di transazione | Intervallo di prezzo ($) | Azioni a fine dichiarazione | % di variazione |
|---|---|---|---|---|---|---|---|
| 2026-06-01 | Dr. Barry S. TichoChief Medical Officer | -1,80k | 54,89k | Automatic Disposition | 30,58 | 34,83k | -4,90% |
| 2026-05-01 | Dr. Barry S. TichoChief Medical Officer | -2,24k | 73,55k | Automatic Disposition | 32,79 | 36,62k | -5,77% |
| 2026-04-01 | Dr. Barry S. TichoChief Medical Officer | -1,84k | 60,03k | Automatic Disposition | 32,66 | 38,86k | -4,52% |
| 2026-03-20 | Mr. Jonathan AllanCorporate Secretary & General Counsel | -9,29k | 313,04k | Automatic Disposition | 33,64 - 34,41 | 19,54k | -32,23% |
| 2026-03-19 | Dr. Barry S. TichoChief Medical Officer | -1,37k | 37,95k | Derivative Exercise and Sale | 2,19 - 29,99 | 40,70k | - |
| 2026-03-17 | Dr. Barry S. TichoChief Medical Officer | -12,85k | 413,02k | Vendita | 31,28 - 33,38 | 40,70k | -24,00% |
| 2026-03-19 | Dr. Barry S. TichoChief Medical Officer | -96,00 | 2,88k | Automatic Disposition | 29,99 | 40,70k | -0,24% |
| 2026-03-17 | Mr. Thomas Edward LeggettCFO | -4,58k | 147,14k | Vendita | 31,28 - 33,38 | 10,17k | -31,04% |
| 2026-03-17 | Mr. Jason HoittChief Patient Officer | -3,71k | 119,31k | Vendita | 31,28 - 33,38 | 10,28k | -26,54% |
| 2026-03-17 | Mr. Jonathan AllanCorporate Secretary & General Counsel | -8,90k | 285,90k | Vendita | 31,28 - 33,38 | 28,84k | -23,57% |
| 2026-03-15 | Mr. Jason HoittChief Patient Officer | 10,00k | 0,00 | Derivative Exercise and Retained Stock | - | 13,99k | 250,75% |
| 2026-03-15 | Mr. Thomas Edward LeggettCFO | 14,75k | 0,00 | Derivative Exercise and Retained Stock | - | 14,75k | - |
| 2026-03-15 | Dr. Edward M. KayeAdvisor & Director | 61,75k | 0,00 | Derivative Exercise and Retained Stock | - | 110,87k | 125,70% |
| 2026-03-15 | Dr. Barry S. TichoChief Medical Officer | 33,85k | 0,00 | Derivative Exercise and Retained Stock | - | 53,65k | 170,98% |
| 2026-03-15 | Mr. Jonathan AllanCorporate Secretary & General Counsel | 25,48k | 0,00 | Derivative Exercise and Retained Stock | - | 37,73k | 207,86% |
| 2026-03-13 | Dr. Arthur A. LevinIndependent Director | -605,00 | 22,26k | Automatic Disposition | 36,80 | 22,22k | -2,65% |
| 2026-03-10 | Dr. Arthur O. TzianabosChairman of the Board | -3,96k | 125,27k | Derivative Exercise and Sale | 8,33 - 40,00 | 31,34k | - |
| 2026-03-10 | Dr. Arthur O. TzianabosChairman of the Board | -400,00 | 16,00k | Automatic Disposition | 40,00 | 31,34k | -1,26% |
| 2026-03-10 | Dr. Adrian R. KrainerCo-Founder & Independent Director | -33,24k | 1,32M | Automatic Disposition | 39,74 | 283,30k | -10,50% |
| 2026-03-02 | Dr. Adrian R. KrainerCo-Founder & Independent Director | -7,23k | 286,72k | Automatic Disposition | 39,66 | 316,55k | -2,23% |
| 2025-12-31 | Dr. Arthur A. LevinIndependent Director | 1,21k | 0,00 | Derivative Exercise and Retained Stock | - | 22,82k | 5,60% |
| 2025-12-08 | Mr. Jonathan AllanCorporate Secretary & General Counsel | -3,98k | 128,41k | Automatic Disposition | 31,60 - 32,61 | 11,83k | -25,16% |
| 2025-12-08 | Dr. Edward M. KayeAdvisor & Director | -13,43k | 433,39k | Automatic Disposition | 31,44 - 33,10 | 49,12k | -21,47% |
| 2025-12-03 | Dr. Barry S. TichoChief Medical Officer | 4,64k | 0,00 | Derivative Exercise and Retained Stock | - | 19,80k | 30,63% |
| 2025-12-03 | Dr. Barry S. TichoChief Medical Officer | -5,36k | 167,12k | Derivative Exercise and Sale | 30,76 - 31,35 | 19,80k | - |
| 2025-12-03 | Dr. Edward M. KayeAdvisor & Director | 11,25k | 0,00 | Derivative Exercise and Retained Stock | - | 62,55k | 21,93% |
| 2025-12-03 | Dr. Edward M. KayeAdvisor & Director | -15,00k | 466,96k | Derivative Exercise and Sale | 30,76 - 31,85 | 62,55k | - |
| 2025-12-03 | Mr. Jonathan AllanCorporate Secretary & General Counsel | -6,00k | 186,53k | Derivative Exercise and Sale | 30,76 - 31,33 | 15,81k | - |
| 2025-12-05 | Mr. Jonathan AllanCorporate Secretary & General Counsel | -3,80k | 119,79k | Automatic Disposition | 31,08 - 31,76 | 15,81k | -19,39% |
| 2025-12-01 | Dr. Barry S. TichoChief Medical Officer | 7,96k | 0,00 | Derivative Exercise and Retained Stock | - | 15,16k | 110,65% |
| 2025-12-01 | Dr. Barry S. TichoChief Medical Officer | -4,02k | 121,47k | Derivative Exercise and Sale | 29,56 - 30,85 | 15,16k | - |
| 2024-12-01 | Dr. Edward M. KayeAdvisor & Director | 2,18k | 0,00 | Derivative Exercise and Retained Stock | - | 51,31k | 4,44% |
| 2024-12-01 | Dr. Edward M. KayeAdvisor & Director | -2,14k | 64,54k | Derivative Exercise and Sale | 29,56 - 30,85 | 51,31k | - |
| 2025-12-01 | Mr. Jonathan AllanCorporate Secretary & General Counsel | 7,78k | 0,00 | Derivative Exercise and Retained Stock | - | 19,61k | 65,77% |
| 2025-12-01 | Mr. Jonathan AllanCorporate Secretary & General Counsel | -4,58k | 138,27k | Derivative Exercise and Sale | 29,56 - 30,85 | 19,61k | - |
| 2025-11-24 | Dr. Adrian R. KrainerCo-Founder & Independent Director | -40,47k | 1,20M | Automatic Disposition | 29,72 | 323,77k | -11,11% |
| 2025-11-14 | Dr. Adrian R. KrainerCo-Founder & Independent Director | -40,47k | 1,09M | Automatic Disposition | 26,61 - 27,34 | 364,25k | -10,00% |
| 2025-11-03 | Dr. Barry S. TichoChief Medical Officer | -5,93k | 152,57k | Automatic Disposition | 25,22 - 29,35 | 7,20k | -45,19% |
| 2025-10-08 | Dr. Edward M. KayeAdvisor & Director | -25,00k | 735,00k | Derivative Exercise and Sale | 0,60 - 30,00 | 49,12k | - |
| 2025-10-03 | Dr. Edward M. KayeAdvisor & Director | -42,46k | 1,07M | Automatic Disposition | 25,09 | 49,12k | -46,36% |
| 2025-10-03 | Mr. Jonathan AllanCorporate Secretary & General Counsel | -10,00k | 159,15k | Derivative Exercise and Sale | 9,15 - 25,07 | 11,83k | - |
| 2025-10-01 | Dr. Barry S. TichoChief Medical Officer | -5,34k | 126,32k | Automatic Disposition | 23,64 | 13,13k | -28,93% |
| 2025-09-30 | Dr. Arthur A. LevinIndependent Director | 1,21k | 0,00 | Derivative Exercise and Retained Stock | - | 21,61k | 5,94% |
| 2025-09-02 | Dr. Barry S. TichoChief Medical Officer | -5,50k | 109,33k | Automatic Disposition | 19,87 | 18,47k | -22,95% |
| 2025-08-29 | Dr. Edward M. KayeAdvisor & Director | -61,89k | 1,25M | Automatic Disposition | 20,00 - 20,14 | 91,59k | -40,32% |
| 2025-08-29 | Mr. Jonathan AllanCorporate Secretary & General Counsel | -10,00k | 130,56k | Derivative Exercise and Sale | 7,07 - 20,14 | 11,83k | - |
| 2025-09-02 | Mr. Jonathan AllanCorporate Secretary & General Counsel | -12,12k | 243,55k | Automatic Disposition | 20,07 - 20,14 | 11,83k | -50,60% |
| 2025-08-22 | Skorpios TrustSocietà | -1.000,00k | 18,50M | Vendita | 18,50 | 2,26M | -30,71% |
| 2025-08-18 | Dr. Barry S. TichoChief Medical Officer | -2,81k | 51,16k | Vendita | 18,24 | 23,97k | -10,48% |
| 2025-08-18 | Dr. Edward M. KayeAdvisor & Director | -12,13k | 221,15k | Vendita | 18,24 | 153,47k | -7,32% |
| 2025-08-18 | Mr. Jonathan AllanCorporate Secretary & General Counsel | -1,68k | 30,69k | Vendita | 18,24 | 23,95k | -6,57% |
| 2025-08-14 | Dr. Barry S. TichoChief Medical Officer | 10,00k | 0,00 | Derivative Exercise and Retained Stock | - | 26,78k | 59,61% |
| 2025-08-14 | Mr. Jonathan AllanCorporate Secretary & General Counsel | 6,00k | 0,00 | Derivative Exercise and Retained Stock | - | 25,63k | 30,56% |
| 2025-08-14 | Dr. Edward M. KayeAdvisor & Director | 26,25k | 0,00 | Derivative Exercise and Retained Stock | - | 165,60k | 18,84% |
| 2025-08-13 | Mr. Jonathan AllanCorporate Secretary & General Counsel | -13,71k | 205,68k | Automatic Disposition | 15,00 | 19,63k | -41,12% |
| 2025-08-01 | Dr. Barry S. TichoChief Medical Officer | -4,50k | 57,72k | Automatic Disposition | 12,82 | 16,78k | -21,17% |
| 2025-07-01 | Dr. Barry S. TichoChief Medical Officer | -4,50k | 52,38k | Automatic Disposition | 11,63 | 21,28k | -17,47% |
| 2025-06-30 | Dr. Arthur A. LevinIndependent Director | 1,21k | 0,00 | Derivative Exercise and Retained Stock | - | 20,40k | 6,31% |
| 2025-06-18 | Skorpios TrustSocietà | -650,00k | 7,15M | Vendita | 11,00 | 3,26M | -16,64% |
| 2025-06-04 | Skorpios TrustSocietà | -3,00M | 30,60M | Vendita | 10,20 | 3,91M | -43,44% |
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