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| Data | Nome del titolare | Azioni transazionate | Intervallo di valore ($) | Tipo di transazione | Intervallo di prezzo ($) | Azioni a fine dichiarazione | % di variazione |
|---|---|---|---|---|---|---|---|
| 2026-05-26 | Mr. David Frank HoffmeisterIndependent Director | 15,00k | 370,35k | Derivative Exercise and Retained Stock | 24,69 | 82,99k | 22,06% |
| 2026-05-14 | Dr. Gilbert H. KlimanIndependent Director | -5,00k | 580,35k | Derivative Exercise and Sale | 24,69 - 140,76 | 32,80k | - |
| 2026-05-11 | Dr. Gilbert H. KlimanIndependent Director | -5,00k | 551,55k | Derivative Exercise and Sale | 24,69 - 135,00 | 32,80k | - |
| 2026-04-30 | Mr. Alex R. ThurmanSenior VP & CFO | -10,00k | 1,01M | Derivative Exercise and Sale | 38,68 - 140,00 | 38,45k | - |
| 2026-05-01 | Mr. Joseph E. GilliamPresident & COO | -19,57k | 2,81M | Vendita | 143,54 | 29,49k | -39,89% |
| 2026-05-01 | Dr. Leana S. WenIndependent Director | -1,70k | 243,70k | Vendita | 143,35 | 17,01k | -9,09% |
| 2026-04-10 | Dr. Tomas NavratilChief Development Officer | -2,09k | 246,18k | Automatic Disposition | 116,72 - 120,23 | 50,58k | -3,97% |
| 2026-04-02 | Dr. Tomas NavratilChief Development Officer | -2,98k | 326,28k | Sale to Issuer | 109,60 | 52,67k | -5,35% |
| 2026-04-02 | Mr. Alex R. ThurmanSenior VP & CFO | -1,59k | 174,15k | Sale to Issuer | 109,60 | 38,45k | -3,97% |
| 2026-04-02 | Mr. Joseph E. GilliamPresident & COO | -3,17k | 347,32k | Sale to Issuer | 109,60 | 49,07k | -6,07% |
| 2026-04-02 | Mr. Thomas William BurnsChairman & CEO | -9,94k | 1,09M | Sale to Issuer | 109,60 | 567,04k | -1,72% |
| 2026-04-01 | Mr. Thomas William BurnsChairman & CEO | -180,31k | 0,00 | Other Disposition | - | 567,04k | -24,13% |
| 2026-03-31 | Dr. Tomas NavratilChief Development Officer | -5,80k | 635,46k | Sale to Issuer | 109,60 | 49,65k | -10,46% |
| 2026-03-25 | Mr. Alex R. ThurmanSenior VP & CFO | -2,51k | 267,32k | Automatic Disposition | 106,46 | 36,74k | -6,40% |
| 2026-03-24 | Mr. Thomas William BurnsChairman & CEO | -2,74k | 288,75k | Sale to Issuer | 105,23 | 1,70M | -0,16% |
| 2026-03-23 | Dr. Tomas NavratilChief Development Officer | -5,17k | 548,69k | Sale to Issuer | 105,23 - 106,84 | 43,75k | -10,58% |
| 2026-03-24 | Mr. Alex R. ThurmanSenior VP & CFO | -1,52k | 160,07k | Automatic Disposition | 105,24 | 39,25k | -3,73% |
| 2026-03-23 | Mr. Alex R. ThurmanSenior VP & CFO | -3,25k | 343,98k | Sale to Issuer | 105,23 - 106,84 | 39,25k | -7,65% |
| 2026-03-23 | Mr. Joseph E. GilliamPresident & COO | -15,12k | 1,60M | Sale to Issuer | 105,23 - 106,84 | 46,41k | -24,57% |
| 2026-03-17 | Mr. Alex R. ThurmanSenior VP & CFO | -625,00 | 61,97k | Automatic Disposition | 99,15 | 36,74k | -1,67% |
| 2026-03-16 | Mr. Alex R. ThurmanSenior VP & CFO | -614,00 | 60,75k | Sale to Issuer | 98,94 | 36,74k | -1,64% |
| 2026-03-16 | Mr. Joseph E. GilliamPresident & COO | -1,19k | 117,64k | Sale to Issuer | 98,94 | 33,67k | -3,41% |
| 2026-03-16 | Mr. Thomas William BurnsChairman & CEO | -2,80k | 277,13k | Sale to Issuer | 98,94 | 1,70M | -0,16% |
| 2026-03-16 | Dr. Tomas NavratilChief Development Officer | -1,03k | 101,08k | Automatic Disposition | 97,33 - 99,05 | 37,94k | -2,65% |
| 2026-03-16 | Dr. Tomas NavratilChief Development Officer | -958,00 | 94,78k | Sale to Issuer | 98,94 | 37,94k | -2,46% |
| 2026-03-13 | Mr. Joseph E. GilliamPresident & COO | -2,46k | 238,86k | Sale to Issuer | 97,02 | 32,72k | -7,00% |
| 2026-03-13 | Dr. Tomas NavratilChief Development Officer | -1,07k | 104,20k | Sale to Issuer | 97,02 | 37,16k | -2,81% |
| 2026-03-13 | Mr. Thomas William BurnsChairman & CEO | -5,21k | 505,67k | Sale to Issuer | 97,02 | 1,69M | -0,31% |
| 2026-03-05 | Dr. Tomas NavratilChief Development Officer | -361,00 | 40,47k | Sale to Issuer | 112,10 | 35,13k | -1,02% |
| 2026-03-05 | Mr. Thomas William BurnsChairman & CEO | -1,10k | 123,09k | Sale to Issuer | 112,10 | 1,69M | -0,06% |
| 2026-02-24 | Mr. Thomas William BurnsChairman & CEO | -4,06k | 483,71k | Sale to Issuer | 119,17 | 1,69M | -0,24% |
| 2026-02-24 | Dr. Tomas NavratilChief Development Officer | -396,00 | 47,19k | Sale to Issuer | 119,17 | 34,47k | -1,14% |
| 2026-02-24 | Mr. Joseph E. GilliamPresident & COO | -1,06k | 125,96k | Sale to Issuer | 119,17 | 30,65k | -3,33% |
| 2026-02-19 | Ms. Aimee S. WeisnerIndependent Director | -15,00k | 1,39M | Derivative Exercise and Sale | 24,69 - 118,56 | 47,58k | - |
| 2026-02-19 | Ms. Aimee S. WeisnerIndependent Director | -980,00 | 0,00 | Other Disposition | - | 47,58k | -2,02% |
| 2026-02-09 | Mr. Thomas William BurnsChairman & CEO | 166,00k | 5,13M | Derivative Exercise and Retained Stock | 30,92 | 1,69M | 10,93% |
| 2026-02-06 | Mr. Thomas William BurnsChairman & CEO | -67,35k | 0,00 | Other Disposition | - | 1,69M | -3,84% |
| 2026-01-22 | Mr. Marc A. StapleyIndependent Director | -15,00k | 1,55M | Derivative Exercise and Sale | 24,69 - 129,78 | 34,61k | - |
| 2026-01-22 | Mr. Joseph E. GilliamPresident & COO | -10,50k | 761,10k | Derivative Exercise and Sale | 55,18 - 129,28 | 29,76k | - |
| 2026-01-21 | Mr. Joseph E. GilliamPresident & COO | -4,50k | 312,75k | Derivative Exercise and Sale | 55,18 - 124,65 | 29,76k | - |
| 2026-01-08 | Mr. Thomas William BurnsChairman & CEO | -275,00k | 27,09M | Derivative Exercise and Sale | 16,49 - 115,00 | 1,52M | - |
| 2025-12-30 | Mr. Thomas William BurnsChairman & CEO | -1,10k | 125,44k | Sale to Issuer | 114,24 | 1,52M | -0,07% |
| 2025-12-30 | Dr. Tomas NavratilChief Development Officer | -510,00 | 58,26k | Sale to Issuer | 114,24 | 33,89k | -1,48% |
| 2025-12-09 | Dr. Gilbert H. KlimanIndependent Director | -5,00k | 412,90k | Derivative Exercise and Sale | 24,69 - 107,27 | 32,34k | - |
| 2025-11-25 | Mr. Alex R. ThurmanSenior VP & CFO | -315,00 | 33,08k | Automatic Disposition | 105,00 | 36,74k | -0,85% |
| 2025-11-18 | Mr. Joseph E. GilliamPresident & COO | -19,34k | 1,74M | Vendita | 90,00 | 29,76k | -39,39% |
| 2025-09-23 | Mr. Joseph E. GilliamPresident & COO | -1,06k | 89,43k | Sale to Issuer | 84,69 | 49,10k | -2,11% |
| 2025-09-23 | Mr. Thomas William BurnsChairman & CEO | -4,06k | 343,76k | Sale to Issuer | 84,69 | 1,52M | -0,27% |
| 2025-09-22 | Dr. Tomas NavratilChief Development Officer | -517,00 | 43,54k | Automatic Disposition | 82,79 - 84,70 | 33,37k | -1,53% |
| 2025-09-23 | Dr. Tomas NavratilChief Development Officer | -483,00 | 40,91k | Sale to Issuer | 84,69 | 33,37k | -1,43% |
| 2025-09-19 | Dr. Tomas NavratilChief Development Officer | -510,00 | 42,57k | Sale to Issuer | 83,47 | 33,40k | -1,50% |
| 2025-09-19 | Mr. Thomas William BurnsChairman & CEO | -1,10k | 91,65k | Sale to Issuer | 83,47 | 1,51M | -0,07% |
| 2025-09-11 | Dr. Tomas NavratilChief Development Officer | -5,14k | 453,62k | Automatic Disposition | 87,98 - 88,61 | 32,88k | -13,52% |
| 2025-06-11 | Mr. David Frank HoffmeisterIndependent Director | 25,00k | 800,00k | Derivative Exercise and Retained Stock | 32,00 | 67,43k | 58,92% |
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