| 2026-04-06 | Mr. John M. GillIndependent Director | 9,20k | 31,35k | Acquisto | 3,41 | 21,70k | 73,60% |
| 2026-04-01 | Mr. Gregory L. WeaverCFO | 10,00k | 31,50k | Acquisto | 3,15 | 38,08k | 35,62% |
| 2026-04-01 | Mr. Jerome Benedict DursoChairman, CEO & President | 15,00k | 47,10k | Acquisto | 3,14 | 47,50k | 46,15% |
| 2026-03-06 | Mr. Gregory L. WeaverCFO | 5,00k | 17,70k | Acquisto | 3,54 | 28,08k | 21,67% |
| 2026-03-06 | Mr. Jerome Benedict DursoChairman, CEO & President | 20,00k | 70,79k | Acquisto | 3,54 | 32,50k | 160,00% |
| 2026-01-30 | Dr. M. Scot RobertsChief Scientific Officer | 11,86k | 0,00 | Derivative Exercise and Retained Stock | - | 112,82k | 11,75% |
| 2026-01-30 | Dr. M. Scot RobertsChief Scientific Officer | -5,19k | 28,94k | Derivative Exercise and Sale | 5,55 - 5,60 | 112,82k | - |
| 2026-01-30 | Dr. Vipin K. GargInsider | 15,14k | 0,00 | Derivative Exercise and Retained Stock | - | 424,52k | 3,70% |
| 2026-01-30 | Dr. Vipin K. GargInsider | -11,63k | 65,14k | Derivative Exercise and Sale | 5,60 | 424,52k | - |
| 2026-01-27 | Mr. Raymond M. JordtChief Business Officer | 11,62k | 0,00 | Derivative Exercise and Retained Stock | - | 65,54k | 21,55% |
| 2026-01-27 | Mr. Raymond M. JordtChief Business Officer | -4,23k | 26,14k | Derivative Exercise and Sale | 6,18 | 65,54k | - |
| 2026-01-27 | Dr. Vipin K. GargInsider | 23,30k | 0,00 | Derivative Exercise and Retained Stock | - | 402,45k | 6,15% |
| 2026-01-27 | Dr. Vipin K. GargInsider | -17,90k | 110,61k | Derivative Exercise and Sale | 6,18 | 402,45k | - |
| 2026-01-27 | Dr. M. Scot RobertsChief Scientific Officer | 11,10k | 0,00 | Derivative Exercise and Retained Stock | - | 95,40k | 13,17% |
| 2026-01-27 | Dr. M. Scot RobertsChief Scientific Officer | -4,75k | 29,34k | Derivative Exercise and Sale | 6,18 | 95,40k | - |
| 2026-01-25 | Mr. Raymond M. JordtChief Business Officer | 10,75k | 0,00 | Derivative Exercise and Retained Stock | - | 53,92k | 24,89% |
| 2026-01-25 | Mr. Raymond M. JordtChief Business Officer | -3,86k | 21,20k | Derivative Exercise and Sale | 5,50 | 53,92k | - |
| 2026-01-25 | Dr. Vipin K. GargInsider | 24,07k | 0,00 | Derivative Exercise and Retained Stock | - | 379,15k | 6,78% |
| 2026-01-25 | Dr. Vipin K. GargInsider | -17,98k | 98,91k | Derivative Exercise and Sale | 5,50 | 379,15k | - |
| 2026-01-25 | Dr. M. Scot RobertsChief Scientific Officer | 10,23k | 0,00 | Derivative Exercise and Retained Stock | - | 84,29k | 13,81% |
| 2026-01-25 | Dr. M. Scot RobertsChief Scientific Officer | -4,37k | 24,05k | Derivative Exercise and Sale | 5,50 | 84,29k | - |
| 2026-01-08 | Mr. Wayne F. PisanoIndependent Director | 5,00k | 20,41k | Acquisto | 4,08 | 13,50k | 58,84% |
| 2026-01-01 | Mr. Raymond M. JordtChief Business Officer | 6,90k | 0,00 | Derivative Exercise and Retained Stock | - | 43,17k | 19,02% |
| 2026-01-01 | Mr. Raymond M. JordtChief Business Officer | -2,48k | 8,93k | Derivative Exercise and Sale | 3,61 | 43,17k | - |
| 2026-01-05 | Dr. Catherine Angell SohnIndependent Director | 500,00 | 2,12k | Acquisto | 4,24 | 1,50k | 50,00% |
| 2025-12-29 | Dr. Diane Kathryn JorkaskyIndependent Director | 527,00 | 2,00k | Acquisto | 3,80 | 527,00 | - |
| 2025-12-23 | Mr. John M. GillIndependent Director | 12,50k | 51,25k | Acquisto | 4,10 | 12,50k | - |
| 2025-12-22 | Mr. Jerome Benedict DursoChairman, CEO & President | 12,50k | 51,57k | Acquisto | 4,13 | 12,50k | - |
| 2025-11-11 | Mr. Gregory L. WeaverCFO | 13,08k | 0,00 | Derivative Exercise and Retained Stock | - | 23,08k | 130,78% |
| 2025-11-11 | Mr. Gregory L. WeaverCFO | -5,67k | 24,28k | Derivative Exercise and Sale | 4,28 | 23,08k | - |
| 2022-01-06 | Mr. John M. GillIndependent Director | -2,71k | 0,00 | Other Disposition | - | 0,00 | -100,00% |