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| Data | Nome del titolare | Azioni transazionate | Intervallo di valore ($) | Tipo di transazione | Intervallo di prezzo ($) | Azioni a fine dichiarazione | % di variazione |
|---|---|---|---|---|---|---|---|
| 2026-06-01 | Mr. Kevin FeeleyCFO | -369,00 | 19,09k | Derivative Exercise and Sale | 51,74 | 35,29k | - |
| 2026-06-01 | Mr. Kevin FeeleyCFO | 348,00 | 0,00 | Derivative Exercise and Retained Stock | - | 35,29k | 1,00% |
| 2026-05-18 | Casdin Capital, LLCSocietà | 500,00k | 21,46M | Acquisto | 42,55 - 43,81 | 3,53M | 16,52% |
| 2026-05-13 | Corvex Management LPSocietà | 351,27k | 13,77M | Acquisto | 38,28 - 39,92 | 4,78M | 7,92% |
| 2026-05-07 | Corvex Management LPSocietà | 1,21M | 46,81M | Acquisto | 35,46 - 41,15 | 4,43M | 37,33% |
| 2026-05-07 | Casdin Capital, LLCSocietà | 850,00k | 0,00 | Open Market Derivative Acquisition | - | 850,00k | - |
| 2026-04-29 | Ms. Katherine A. StuelandPresident, CEO & Director | -2,17k | 141,59k | Derivative Exercise and Sale | 64,12 - 65,20 | 93,22k | - |
| 2026-04-29 | Ms. Katherine A. StuelandPresident, CEO & Director | 1,70k | 0,00 | Derivative Exercise and Retained Stock | - | 93,22k | 1,86% |
| 2026-04-29 | Mr. Kevin FeeleyCFO | -392,00 | 25,56k | Derivative Exercise and Sale | 65,19 | 34,94k | - |
| 2026-04-29 | Mr. Kevin FeeleyCFO | 362,00 | 0,00 | Derivative Exercise and Retained Stock | - | 34,94k | 1,05% |
| 2026-03-26 | Mr. Kevin FeeleyCFO | 7,43k | 0,00 | Derivative Exercise and Retained Stock | - | 34,58k | 27,38% |
| 2026-03-26 | Mr. Kevin FeeleyCFO | -8,82k | 557,05k | Derivative Exercise and Sale | 61,29 - 65,21 | 34,58k | - |
| 2026-03-26 | Ms. Katherine A. StuelandPresident, CEO & Director | 33,07k | 0,00 | Derivative Exercise and Retained Stock | - | 91,51k | 56,58% |
| 2026-03-26 | Ms. Katherine A. StuelandPresident, CEO & Director | -46,93k | 2,96M | Derivative Exercise and Sale | 61,29 - 65,21 | 91,51k | - |
| 2026-03-15 | Ms. Katherine A. StuelandPresident, CEO & Director | 13,49k | 0,00 | Derivative Exercise and Retained Stock | - | 58,45k | 30,01% |
| 2026-03-16 | Ms. Katherine A. StuelandPresident, CEO & Director | -17,18k | 1,32M | Derivative Exercise and Sale | 76,35 - 77,94 | 58,45k | - |
| 2026-03-15 | Mr. Kevin FeeleyCFO | 5,31k | 0,00 | Derivative Exercise and Retained Stock | - | 27,15k | 24,29% |
| 2026-03-16 | Mr. Kevin FeeleyCFO | -5,71k | 438,20k | Derivative Exercise and Sale | 76,35 - 77,94 | 27,15k | - |
| 2026-03-09 | Mr. Kevin FeeleyCFO | 1,18k | 0,00 | Derivative Exercise and Retained Stock | - | 21,84k | 5,72% |
| 2026-03-09 | Mr. Kevin FeeleyCFO | -1,28k | 111,05k | Derivative Exercise and Sale | 86,75 | 21,84k | - |
| 2026-03-09 | Ms. Katherine A. StuelandPresident, CEO & Director | 2,87k | 0,00 | Derivative Exercise and Retained Stock | - | 44,96k | 6,81% |
| 2026-03-09 | Ms. Katherine A. StuelandPresident, CEO & Director | -3,68k | 319,06k | Derivative Exercise and Sale | 86,75 | 44,96k | - |
| 2026-03-03 | Corvex Management LPSocietà | 169,52k | 13,46M | Acquisto | 70,34 - 82,06 | 3,23M | 5,54% |
| 2026-03-04 | Mr. Kevin FeeleyCFO | -6,19k | 486,37k | Vendita | 77,63 - 79,25 | 18,67k | -24,89% |
| 2026-03-04 | Ms. Katherine A. StuelandPresident, CEO & Director | -25,46k | 2,00M | Vendita | 77,63 - 79,25 | 38,68k | -39,69% |
| 2026-03-01 | Mr. Kevin FeeleyCFO | 431,00 | 0,00 | Derivative Exercise and Retained Stock | - | 9,60k | 4,70% |
| 2026-03-01 | Mr. Kevin FeeleyCFO | -287,00 | 22,25k | Derivative Exercise and Sale | 77,52 | 9,60k | - |
| 2026-02-04 | Dr. Bryan M. DechairoCOO | -5,96k | 510,87k | Automatic Disposition | 83,04 - 91,92 | 0,00 | -100,00% |
| 2026-02-01 | Dr. Bryan M. DechairoCOO | 5,96k | 0,00 | Derivative Exercise and Retained Stock | - | 5,96k | - |
| 2026-02-01 | Dr. Bryan M. DechairoCOO | -3,41k | 339,68k | Derivative Exercise and Sale | 96,77 - 100,31 | 5,96k | - |
| 2026-01-29 | Mr. Kevin FeeleyCFO | 437,00 | 0,00 | Derivative Exercise and Retained Stock | - | 9,17k | 5,01% |
| 2026-01-29 | Mr. Kevin FeeleyCFO | -317,00 | 29,79k | Derivative Exercise and Sale | 92,06 - 94,00 | 9,17k | - |
| 2026-01-29 | Ms. Katherine A. StuelandPresident, CEO & Director | 2,22k | 0,00 | Derivative Exercise and Retained Stock | - | 16,46k | 15,60% |
| 2026-01-29 | Ms. Katherine A. StuelandPresident, CEO & Director | -1,65k | 155,37k | Derivative Exercise and Sale | 94,00 | 16,46k | - |
| 2025-12-16 | Mr. Kevin FeeleyCFO | 3,34k | 0,00 | Derivative Exercise and Retained Stock | - | 8,73k | 62,02% |
| 2025-12-16 | Mr. Kevin FeeleyCFO | -3,86k | 554,62k | Derivative Exercise and Sale | 138,93 - 150,75 | 8,73k | - |
| 2025-12-16 | Ms. Katherine A. StuelandPresident, CEO & Director | 7,89k | 0,00 | Derivative Exercise and Retained Stock | - | 14,24k | 124,42% |
| 2025-12-16 | Ms. Katherine A. StuelandPresident, CEO & Director | -10,86k | 1,56M | Derivative Exercise and Sale | 138,93 - 150,75 | 14,24k | - |
| 2025-12-09 | Mr. Kevin FeeleyCFO | 1,20k | 0,00 | Derivative Exercise and Retained Stock | - | 5,39k | 28,52% |
| 2025-12-09 | Mr. Kevin FeeleyCFO | -1,27k | 201,65k | Derivative Exercise and Sale | 159,28 | 5,39k | - |
| 2025-12-09 | Ms. Katherine A. StuelandPresident, CEO & Director | 2,91k | 0,00 | Derivative Exercise and Retained Stock | - | 6,34k | 84,63% |
| 2025-12-09 | Ms. Katherine A. StuelandPresident, CEO & Director | -3,64k | 579,62k | Derivative Exercise and Sale | 159,28 | 6,34k | - |
| 2025-12-01 | Mr. Kevin FeeleyCFO | 340,00 | 0,00 | Derivative Exercise and Retained Stock | - | 4,19k | 8,82% |
| 2025-12-01 | Mr. Kevin FeeleyCFO | -377,00 | 61,28k | Derivative Exercise and Sale | 162,54 | 4,19k | - |
| 2025-11-24 | Mr. Joshua RuchIndependent Director | -38,00k | 6,09M | Vendita | 158,40 - 162,04 | 156,27k | -19,56% |
| 2025-10-29 | Ms. Katherine A. StuelandPresident, CEO & Director | 1,72k | 0,00 | Derivative Exercise and Retained Stock | - | 3,44k | 99,77% |
| 2025-10-29 | Ms. Katherine A. StuelandPresident, CEO & Director | -2,16k | 294,65k | Derivative Exercise and Sale | 136,54 - 136,75 | 3,44k | - |
| 2025-10-29 | Mr. Kevin FeeleyCFO | 365,00 | 0,00 | Derivative Exercise and Retained Stock | - | 3,76k | 10,76% |
| 2025-10-29 | Mr. Kevin FeeleyCFO | -388,00 | 52,98k | Derivative Exercise and Sale | 136,54 | 3,76k | - |
| 2025-09-30 | Ms. Katherine A. StuelandPresident, CEO & Director | -12,86k | 1,39M | Automatic Disposition | 105,10 - 113,68 | 1,72k | -88,20% |
| 2025-09-30 | Mr. Kevin FeeleyCFO | -1,25k | 92,31k | Derivative Exercise and Sale | 32,67 - 107,68 | 3,39k | - |
| 2025-09-30 | Mr. Kevin FeeleyCFO | -5,36k | 583,25k | Automatic Disposition | 107,68 - 113,68 | 3,39k | -61,26% |
| 2025-09-16 | Mr. Kevin FeeleyCFO | 7,20k | 0,00 | Derivative Exercise and Retained Stock | - | 12,48k | 136,15% |
| 2025-09-16 | Ms. Katherine A. StuelandPresident, CEO & Director | 8,25k | 0,00 | Derivative Exercise and Retained Stock | - | 14,58k | 130,34% |
| 2025-09-16 | Ms. Katherine A. StuelandPresident, CEO & Director | -10,50k | 1,28M | Derivative Exercise and Sale | 121,47 | 14,58k | - |
| 2025-09-16 | Mr. Kevin FeeleyCFO | -3,73k | 452,85k | Vendita | 121,47 | 12,48k | -23,00% |
| 2025-09-09 | Mr. Kevin FeeleyCFO | 1,19k | 0,00 | Derivative Exercise and Retained Stock | - | 5,29k | 29,05% |
| 2025-09-09 | Mr. Kevin FeeleyCFO | -1,27k | 162,89k | Derivative Exercise and Sale | 128,05 - 129,09 | 5,29k | - |
| 2025-09-09 | Ms. Katherine A. StuelandPresident, CEO & Director | 2,89k | 0,00 | Derivative Exercise and Retained Stock | - | 6,33k | 83,98% |
| 2025-09-09 | Ms. Katherine A. StuelandPresident, CEO & Director | -3,66k | 468,30k | Derivative Exercise and Sale | 128,05 - 129,08 | 6,33k | - |
| 2025-09-01 | Mr. Kevin FeeleyCFO | 339,00 | 0,00 | Derivative Exercise and Retained Stock | - | 4,10k | 9,02% |
| 2025-09-01 | Mr. Kevin FeeleyCFO | -378,00 | 47,56k | Derivative Exercise and Sale | 125,81 | 4,10k | - |
| 2025-08-27 | Mr. Jason RyanChairman of the Board | -39,22k | 5,00M | Vendita | 125,07 - 130,01 | 115,19k | -25,40% |
| 2025-08-22 | Casdin Capital, LLCSocietà | -500,00k | 60,45M | Vendita | 120,90 | 3,03M | -14,18% |
| 2025-06-18 | Mr. Eli Decatur CasdinIndependent Director | 12,92k | 0,00 | Derivative Exercise and Retained Stock | - | 20,52k | 170,19% |
| 2025-07-29 | Mr. Kevin FeeleyCFO | 365,00 | 0,00 | Derivative Exercise and Retained Stock | - | 3,76k | 10,76% |
| 2025-07-29 | Mr. Kevin FeeleyCFO | -388,00 | 40,86k | Derivative Exercise and Sale | 105,31 | 3,76k | - |
| 2025-07-29 | Ms. Katherine A. StuelandPresident, CEO & Director | 1,72k | 0,00 | Derivative Exercise and Retained Stock | - | 3,44k | 100,00% |
| 2025-07-29 | Ms. Katherine A. StuelandPresident, CEO & Director | -2,15k | 226,84k | Derivative Exercise and Sale | 105,31 | 3,44k | - |
| 2025-07-09 | Mr. Kevin FeeleyCFO | -1,25k | 75,11k | Derivative Exercise and Sale | 32,67 - 93,00 | 3,39k | - |
| 2025-07-09 | Mr. Kevin FeeleyCFO | -4,03k | 375,07k | Automatic Disposition | 93,00 | 3,39k | -54,32% |
| 2025-07-09 | Ms. Katherine A. StuelandPresident, CEO & Director | -3,22k | 299,46k | Automatic Disposition | 93,00 | 1,72k | -65,18% |
| 2025-07-01 | Ms. Katherine A. StuelandPresident, CEO & Director | -9,66k | 878,18k | Automatic Disposition | 90,68 - 92,46 | 4,94k | -66,16% |
| 2025-07-01 | Mr. Kevin FeeleyCFO | -1,34k | 122,47k | Automatic Disposition | 90,86 - 91,88 | 7,43k | -15,33% |
| 2025-06-18 | Mr. Keith Arlyn MeisterIndependent Director | 12,92k | 0,00 | Derivative Exercise and Retained Stock | - | 20,13k | 179,38% |
| 2025-06-18 | Mr. Jason RyanChairman of the Board | 12,92k | 0,00 | Derivative Exercise and Retained Stock | - | 154,41k | 9,13% |
| 2025-06-18 | Dr. Emily Marine LeproustIndependent Director | 12,92k | 0,00 | Derivative Exercise and Retained Stock | - | 21,28k | 154,74% |
| 2025-06-18 | Mr. Richard C. PfennigerIndependent Director | 12,92k | 0,00 | Derivative Exercise and Retained Stock | - | 41,51k | 45,22% |
| 2025-06-18 | Rho Capital Partners, Inc.Società | 12,92k | 0,00 | Derivative Exercise and Retained Stock | - | 29,72k | 76,93% |
| 2025-06-16 | Ms. Katherine A. StuelandPresident, CEO & Director | 8,25k | 0,00 | Derivative Exercise and Retained Stock | - | 14,60k | 129,95% |
| 2025-06-16 | Ms. Katherine A. StuelandPresident, CEO & Director | -10,50k | 680,18k | Derivative Exercise and Sale | 64,77 | 14,60k | - |
| 2025-06-16 | Mr. Kevin FeeleyCFO | 3,47k | 0,00 | Derivative Exercise and Retained Stock | - | 8,77k | 65,42% |
| 2025-06-16 | Mr. Kevin FeeleyCFO | -3,73k | 241,54k | Derivative Exercise and Sale | 64,77 | 8,77k | - |
| 2025-06-09 | Mr. Kevin FeeleyCFO | 1,20k | 0,00 | Derivative Exercise and Retained Stock | - | 5,30k | 29,14% |
| 2025-06-09 | Mr. Kevin FeeleyCFO | -1,27k | 91,85k | Derivative Exercise and Sale | 72,55 | 5,30k | - |
| 2025-06-09 | Ms. Katherine A. StuelandPresident, CEO & Director | 2,91k | 0,00 | Derivative Exercise and Retained Stock | - | 6,35k | 84,53% |
| 2025-06-09 | Ms. Katherine A. StuelandPresident, CEO & Director | -3,64k | 264,01k | Derivative Exercise and Sale | 72,55 | 6,35k | - |
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