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| Data | Nome del titolare | Azioni transazionate | Intervallo di valore ($) | Tipo di transazione | Intervallo di prezzo ($) | Azioni a fine dichiarazione | % di variazione |
|---|---|---|---|---|---|---|---|
| 2026-06-04 | Dr. Neil KumarCo-Founder, CEO & Director | -80,00k | 5,41M | Automatic Disposition | 65,72 - 68,96 | 5,08M | -1,55% |
| 2026-05-21 | Dr. Neil KumarCo-Founder, CEO & Director | -26,10k | 1,81M | Automatic Disposition | 67,57 - 70,92 | 5,16M | -0,50% |
| 2026-05-18 | Dr. Thomas TrimarchiCFO & President | -13,65k | 888,42k | Automatic Disposition | 64,82 - 65,95 | 359,19k | -3,66% |
| 2026-05-16 | Dr. Thomas TrimarchiCFO & President | -22,78k | 1,51M | Sale to Issuer | 66,13 | 359,19k | -5,96% |
| 2026-05-16 | Dr. Neil KumarCo-Founder, CEO & Director | 34,98k | 0,00 | Derivative Exercise and Retained Stock | - | 5,18M | 0,68% |
| 2026-05-16 | Dr. Neil KumarCo-Founder, CEO & Director | -36,24k | 2,40M | Derivative Exercise and Sale | 66,13 | 5,18M | - |
| 2026-05-16 | Ms. Maricel M. ApuliCAO | -4,71k | 311,74k | Sale to Issuer | 66,13 | 129,40k | -3,51% |
| 2026-05-15 | Mr. Randal W. ScottIndependent Director | -10,00k | 503,96k | Derivative Exercise and Sale | 16,75 - 69,12 | 9,00k | - |
| 2026-05-07 | Dr. Neil KumarCo-Founder, CEO & Director | -80,00k | 5,39M | Automatic Disposition | 66,65 - 69,09 | 5,15M | -1,53% |
| 2026-04-30 | Ms. Maricel M. ApuliCAO | -2,00k | 143,16k | Automatic Disposition | 71,58 | 102,20k | -1,92% |
| 2026-04-09 | Dr. Neil KumarCo-Founder, CEO & Director | -80,00k | 5,97M | Automatic Disposition | 73,64 - 75,55 | 5,23M | -1,51% |
| 2026-02-18 | Viking Global Investors LPSocietà | -1,18M | 81,29M | Vendita | 67,10 - 76,46 | 11,84M | -9,09% |
| 2026-03-12 | Dr. Neil KumarCo-Founder, CEO & Director | -80,00k | 5,50M | Automatic Disposition | 68,36 - 70,15 | 5,07M | -1,55% |
| 2026-03-10 | Dr. Hannah A. ValantineIndependent Director | -8,67k | 387,07k | Derivative Exercise and Sale | 27,36 - 72,00 | 1,27k | - |
| 2026-03-04 | Ms. Andrea John EllisIndependent Director | -64,92k | 3,66M | Derivative Exercise and Sale | 8,45 - 64,87 | 12,00k | - |
| 2026-02-27 | Dr. Hannah A. ValantineIndependent Director | -25,48k | 483,08k | Derivative Exercise and Sale | 48,45 - 67,84 | 1,27k | - |
| 2026-02-26 | Ms. Maricel M. ApuliCAO | -2,00k | 132,00k | Automatic Disposition | 66,00 | 104,20k | -1,88% |
| 2026-02-19 | Dr. Neil KumarCo-Founder, CEO & Director | -28,05k | 2,00M | Automatic Disposition | 71,03 - 72,80 | 5,39M | -0,52% |
| 2026-02-16 | Dr. Neil KumarCo-Founder, CEO & Director | 33,73k | 0,00 | Derivative Exercise and Retained Stock | - | 5,42M | 0,63% |
| 2026-02-16 | Dr. Neil KumarCo-Founder, CEO & Director | -30,97k | 2,33M | Derivative Exercise and Sale | 75,25 | 5,42M | - |
| 2026-02-17 | Ms. Maricel M. ApuliCAO | -510,00 | 37,90k | Automatic Disposition | 74,31 | 106,20k | -0,48% |
| 2026-02-16 | Ms. Maricel M. ApuliCAO | -4,35k | 327,26k | Sale to Issuer | 75,25 | 106,20k | -3,93% |
| 2026-02-17 | Dr. Thomas TrimarchiCFO & President | -13,60k | 1,02M | Automatic Disposition | 74,71 - 75,38 | 336,59k | -3,88% |
| 2026-02-16 | Dr. Thomas TrimarchiCFO & President | -18,82k | 1,42M | Sale to Issuer | 75,25 | 336,59k | -5,30% |
| 2026-02-17 | Mr. Randal W. ScottIndependent Director | -10,00k | 587,06k | Derivative Exercise and Sale | 16,75 - 75,93 | 9,00k | - |
| 2026-01-13 | Viking Global Investors LPSocietà | -1,37M | 107,33M | Vendita | 76,08 - 84,94 | 13,03M | -9,50% |
| 2026-02-10 | Dr. Neil KumarCo-Founder, CEO & Director | -80,00k | 5,75M | Automatic Disposition | 70,69 - 73,25 | 9,88M | -0,80% |
| 2026-01-08 | Dr. Neil KumarCo-Founder, CEO & Director | -80,00k | 6,04M | Automatic Disposition | 73,64 - 78,19 | 5,46M | -1,44% |
| 2025-12-12 | Dr. Neil KumarCo-Founder, CEO & Director | -60,98k | 4,57M | Derivative Exercise and Sale | 74,60 - 75,24 | 5,54M | - |
| 2025-12-12 | Dr. Thomas TrimarchiCFO & President | -13,83k | 1,04M | Sale to Issuer | 75,15 | 369,00k | -3,61% |
| 2025-12-12 | Ms. Maricel M. ApuliCAO | -2,00k | 150,53k | Sale to Issuer | 75,15 | 109,07k | -1,80% |
| 2025-12-08 | Ms. Maricel M. ApuliCAO | -2,00k | 148,52k | Automatic Disposition | 74,26 | 111,07k | -1,77% |
| 2025-12-04 | Dr. Neil KumarCo-Founder, CEO & Director | -80,00k | 5,91M | Automatic Disposition | 73,04 - 74,80 | 5,54M | -1,42% |
| 2025-11-20 | Dr. Neil KumarCo-Founder, CEO & Director | -26,16k | 1,72M | Automatic Disposition | 64,97 - 66,71 | 5,62M | -0,46% |
| 2025-11-17 | Dr. Wen-Chaun LoIndependent Director | -95,60k | 6,32M | Vendita | 65,23 - 67,06 | 58,08k | -62,21% |
| 2025-11-17 | Mr. Randal W. ScottIndependent Director | -10,00k | 498,97k | Derivative Exercise and Sale | 16,75 - 66,89 | 9,00k | - |
| 2025-11-16 | Dr. Neil KumarCo-Founder, CEO & Director | 31,84k | 0,00 | Derivative Exercise and Retained Stock | - | 5,65M | 0,57% |
| 2025-11-16 | Dr. Neil KumarCo-Founder, CEO & Director | -32,86k | 2,18M | Derivative Exercise and Sale | 66,39 | 5,65M | - |
| 2025-11-17 | Dr. Thomas TrimarchiCFO & President | -16,93k | 1,13M | Automatic Disposition | 66,19 - 66,84 | 382,83k | -4,24% |
| 2025-11-16 | Dr. Thomas TrimarchiCFO & President | -21,32k | 1,42M | Sale to Issuer | 66,39 | 382,83k | -5,27% |
| 2025-11-16 | Ms. Maricel M. ApuliCAO | -4,78k | 317,41k | Sale to Issuer | 66,39 | 113,07k | -4,06% |
| 2025-09-29 | Viking Global Investors LPSocietà | -374,92k | 19,81M | Vendita | 51,67 - 57,13 | 15,89M | -2,30% |
| 2025-11-12 | Dr. Hannah A. ValantineIndependent Director | -25,48k | 449,03k | Derivative Exercise and Sale | 48,45 - 66,07 | 1,27k | - |
| 2025-11-06 | Dr. Neil KumarCo-Founder, CEO & Director | -80,00k | 4,98M | Automatic Disposition | 61,13 - 64,39 | 5,62M | -1,40% |
| 2025-11-06 | Mr. Ronald J. DanielsIndependent Director | -61,03k | 1,77M | Derivative Exercise and Sale | 34,65 - 63,72 | 10,40k | - |
| 2025-10-29 | Dr. Frank P. McCormickCo-Founder, Chairman of Oncology & Director | -198,36k | 13,21M | Automatic Disposition | 65,48 - 69,24 | 756,67k | -20,77% |
| 2025-10-27 | Dr. Frank P. McCormickCo-Founder, Chairman of Oncology & Director | -1,64k | 106,67k | Automatic Disposition | 65,00 | 955,02k | -0,17% |
| 2025-10-08 | Dr. Neil KumarCo-Founder, CEO & Director | -80,00k | 4,38M | Automatic Disposition | 54,39 - 55,09 | 5,70M | -1,38% |
| 2025-09-05 | Dr. Frank P. McCormickCo-Founder, Chairman of Oncology & Director | -74,00k | 3,05M | Derivative Exercise and Sale | 11,92 - 53,16 | 956,67k | - |
| 2025-09-04 | Dr. Neil KumarCo-Founder, CEO & Director | -80,00k | 4,18M | Automatic Disposition | 51,15 - 53,80 | 5,78M | -1,37% |
| 2025-08-21 | Dr. Thomas TrimarchiCFO & President | -42,24k | 2,09M | Vendita | 49,48 | 421,08k | -9,12% |
| 2025-08-20 | Dr. Neil KumarCo-Founder, CEO & Director | -26,16k | 1,28M | Automatic Disposition | 48,81 - 49,25 | 5,86M | -0,44% |
| 2025-08-16 | Ms. Maricel M. ApuliCAO | -4,78k | 245,36k | Sale to Issuer | 51,32 | 124,31k | -3,70% |
| 2025-08-18 | Dr. Thomas TrimarchiCFO & President | -17,35k | 871,72k | Automatic Disposition | 50,14 - 50,94 | 463,32k | -3,61% |
| 2025-08-16 | Dr. Thomas TrimarchiCFO & President | -21,32k | 1,09M | Sale to Issuer | 51,32 | 463,32k | -4,40% |
| 2025-08-16 | Dr. Neil KumarCo-Founder, CEO & Director | 31,84k | 0,00 | Derivative Exercise and Retained Stock | - | 5,88M | 0,54% |
| 2025-08-16 | Dr. Neil KumarCo-Founder, CEO & Director | -32,86k | 1,69M | Derivative Exercise and Sale | 51,32 | 5,88M | - |
| 2025-07-09 | Viking Global Investors LPSocietà | 9,37k | 424,77k | Acquisto | 45,07 - 45,72 | 17,57M | 0,05% |
| 2025-07-15 | Viking Global Investors LPSocietà | -832,11k | 39,46M | Vendita | 45,61 - 47,68 | 17,57M | -4,52% |
| 2025-08-08 | Dr. Charles J. HomcyCo-Founder, Chairman of Pharmaceuticals & Independent Lead Director | -300,00k | 13,91M | Automatic Disposition | 45,87 - 48,00 | 910,09k | -24,79% |
| 2025-08-07 | Ms. Maricel M. ApuliCAO | -1.000,00 | 45,44k | Vendita | 45,44 | 119,68k | -0,83% |
| 2025-08-07 | Dr. Neil KumarCo-Founder, CEO & Director | -80,00k | 3,67M | Automatic Disposition | 45,09 - 46,71 | 5,85M | -1,35% |
| 2025-08-05 | Ms. Andrea John EllisIndependent Director | -17,17k | 553,64k | Derivative Exercise and Sale | 16,75 - 49,00 | 12,00k | - |
| 2025-07-01 | Dr. Neil KumarCo-Founder, CEO & Director | -80,00k | 3,41M | Automatic Disposition | 42,50 - 42,89 | 5,93M | -1,33% |
| 2025-07-01 | Viking Global Investors LPSocietà | 64,19k | 2,71M | Acquisto | 42,15 - 42,28 | 180,04k | 55,41% |
| 2025-07-01 | Viking Global Investors LPSocietà | -16,64k | 701,46k | Vendita | 42,15 | 180,04k | -8,46% |
| 2025-06-27 | Viking Global Investors LPSocietà | -3,50M | 154,00M | Vendita | 44,00 | 18,22M | -16,11% |
| 2025-06-27 | Dr. Charles J. HomcyCo-Founder, Chairman of Pharmaceuticals & Independent Lead Director | -20,00k | 0,00 | Other Disposition | - | 1,21M | -1,63% |
| 2025-06-26 | Dr. Hannah A. ValantineIndependent Director | -4,71k | 207,33k | Vendita | 44,01 - 44,13 | 1,27k | -78,70% |
| 2021-12-29 | Dr. Hannah A. ValantineIndependent Director | 3,52k | 50,05k | Acquisto | 14,23 - 14,24 | 5,98k | 142,64% |
| 2021-12-28 | Dr. Hannah A. ValantineIndependent Director | 4,23k | 54,95k | Acquisto | 12,68 - 13,18 | 4,23k | - |
| 2025-06-24 | Dr. Frank P. McCormickCo-Founder, Chairman of Oncology & Director | -100,00k | 4,42M | Automatic Disposition | 44,23 | 956,67k | -9,46% |
| 2025-06-10 | Dr. Hannah A. ValantineIndependent Director | -4,29k | 99,79k | Derivative Exercise and Sale | 16,75 - 40,00 | 5,20k | - |
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