AMED Amedeo Res

RNS No 2390j
MERRILL LYNCH INTERNATIONAL
12 July 1999

AMENDMENT


                                                           FORM 38.5 (SUMMARY)
                                  

Lodge with Company Announcements Office and the Panel.  Use a separate form   
for each class of securities in which dealings have been made.                
                  


                       CONNECTED EXEMPT MARKET-MAKERS:                        
          
    DISCLOSURE UNDER RULE 38.5 OF THE CITY CODE ON TAKEOVERS AND MERGERS      
                            



Name of EMM                   Merrill Lynch International                      


Date of disclosure            July 12, 1999                     


Contact name                  Linda Blatt                     


Telephone number              0171 772 1040                      


Please see attached disclosure of dealings under Rule 38.5 in the securities  
of the following companies:                                   

Chiroscience Group plc                                   


AMENDMENT                                   

If the attached Rule 38.5 disclosure is to amend a previous disclosure, please
state which element(s) of previous disclosure was incorrect:                  
                

Chiroscience Group plc (08/07/99) - amendment to shares bought                
                                   
                                   
In the case of option business or dealings in derivatives full details should 
be given on a separate sheet so that the nature of the dealings can be fully  
understood.  For options this should include the number of securities under   
option, the exercise period (or in the case of exercise, the exercise date),  
the exercise price and any option money paid or received.  For derivatives    
this should include, at least, the number of reference securities to which    
they relate (when relevant), the maturity date (or if applicable the closing  
out date) and the reference price.                                   

For full details of disclosure requirements see Rules 8 and 38 of the Code.   
If in doubt contact the Monitoring Section of the Panel,                      
Tel. No: 0171 638 0129                                   

                                   
AMENDMENT                                   
                                                                     FORM 38.5
                                  


                          CONNECTED EXEMPT MARKET-MAKERS:                     
             
     DISCLOSURE UNDER RULE 38.5 OF THE CITY CODE ON TAKEOVERS AND MERGERS     
                             

                                   
                                   
Dealing in                      Chiroscience Group plc                     

Class of security               Ordinary                     

Date of disclosure              12/7/1999                     

Date of dealing                 8/7/1999                     

Name of EMM                     Merrill Lynch International                   
               

Name of offeree/offeror with whom connected  Chiroscience Group plc       


Total number of securities purchased                            4,386       
                                   
Highest price paid*                                             #3.00       
                                   
Lowest price paid*                                              #2.97       
                                   
                                   
Total number of securities sold                                 1,000       
                                   
Highest price received*                                         #3.05       
                                   
Lowest price received*                                          #3.05       


*Currency must be stated                                   
                                                                      
                                   
END                                 

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