RNS Number:1716A
Bionostics PLC
12 July 2007


Financial Services Authority

                TR-1i: NOTIFICATION OF MAJOR INTERESTS IN SHARES

1. Identity of the issuer or the                         Bionostics PLC
underlying issuer of existing shares
to which voting rights are attached ii:

2. Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights                       (x)
An acquisition or disposal of financial instruments which may     
result in the acquisition of shares already issued to which       ( )
voting rights are attached
An event changing the breakdown of voting rights                  ( )
Other (please specify):                                           ( )

3. Full name of person(s) subject to                      Barclays PLC
the notification obligationiii:

4. Full name of shareholder(s) (if different from 3.)

Barclays Global Investors Ltd
Barclays Life Assurance Co Ltd
Barclays Stockbrokers Ltd
Gerrard Investment Management Ltd

5. Date of the transaction and date on which the         03 July 2007
threshold is crossed or reached v:

6. Date on which issuer notified:                        04 July 2007

7. Threshold(s) that is/are crossed or reached:          10% to 9%

8. Notified details:
A. Voting rights attached to shares
Class/type         Situation previous to   Resulting situation after the triggering
of shares          the Triggering          transaction viii
                   transaction vi
if possible        Number of   Number of   Number of   Number of Voting   % of voting
using the ISIN     Shares      Voting      Shares      Rights             rights
CODE                           Rights
                               viii
                                                       Direct Indirect    Direct   Indirect
                                                       x      xi
GB0008381823       5,043,071   5,043,071   4,562,866   0      4,562,866   0.00     9.05

B: Financial Instruments
Resulting situation after the triggering transaction xiii
Type of         Expiration    Exercise/           Number of voting   % of voting
financial       date xiii     Conversion Period   rights that may    rights
instrument                    /Date xiv           be acquired if
                                                  the instrument
                                                  is exercised/
                                                  converted

Total (A+B)
Number of voting rights                 % of voting rights
4,562,866                               9.05

9. Chain of controlled undertakings through which the voting rights and/or
the financial instruments are effectively held, if applicable xv:
Barclays Global Investors Ltd
Barclays Life Assurance Co Ltd
Barclays Stockbrokers Ltd
Gerrard Investment Management Ltd

Proxy Voting:
10. Name of the proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold rights:

13. Additional information:

14. Contact Name:                                        Kelly A. Winn, Bionostics PLC

15. Contact Telephone Number                             01993-885070




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