BIO Bionostics

RNS Number:7885E
Bionostics PLC
28 September 2007



Form TR-1 with annex, FSA Version 2.1 updated April 2007

For filings with the FSA include the annex
For filings with issuer exclude the

+---------------------------------------------------------------------------+
|TR-1: Notifications of Major Interests in Shares                           |
+-------------------------------------+-------------------------------------+
|1. Identity of the issuer or the     | Bionostics PLC                      |
|underlying issuer of existing shares |                                     |
|to which voting rights are attached: |                                     |
+-------------------------------------+-------------------------------------+
|                                                                           |
|2. Reason for the notification (yes/no)                                    |
|                                                                           |
+--------------------------------------------------------------+------------+
|An acquisition or disposal of voting rights                   |            |
+--------------------------------------------------------------+------------+
|An acquisition or disposal of financial instruments which may |            |
|result in the acquisition of shares already issued to which   |            |
|voting rights are attached                                    |            |
+--------------------------------------------------------------+------------+
|An event changing the breakdown of voting rights              |    Yes     |
+--------------------------------------------------------------+------------+
|Other (please specify):                                       |            |
+-------------------------------------+------------------------+------------+
|3. Full name of person(s) subject to |North Atlantic Value LLP (an         |
|the notification obligation:         |investment manager/advisor)          |
+-------------------------------------+-------------------------------------+
|4. Full name of shareholder(s) (if   |                                     |
|different from 3)                    |(i)   North Atlantic                 |
|                                     |      Smaller Companies              |
|                                     |      Investment Trust PLC           |
|                                     |(ii)  North Atlantic                 |
|                                     |      Value LLP (as                  |
|                                     |      Investment Adviser to          |
|                                     |      the Trident North Atlantic     |
|                                     |      Fund)                          |
|                                     |(iii) North Atlantic                 |
|                                     |      Value LLP (as Investment       |
|                                     |      Manager/Adviser to other fund  |
|                                     |      management clients)            |
|                                     |(iv)  Oryx International             |
|                                     |      Growth Fund Limited            |
+-------------------------------------+----------+--------------------------+
|5. Date of the transaction (and date on which   |    27 September 2007     |
|the threshold is crossed or reached if          |                          |
|different):                                     |                          |
+------------------------------------------------+--------------------------+
|6. Date on which issuer notified:               |    28 September 2007     |
+------------------------------------------------+--------------------------+
|7. Threshold(s) that is/are crossed or reached: | Overall holding remains  |
|                                                |   the same. Individual   |
|                                                |  shareholding increased  |
|                                                |   through 5% due to an   |
|                                                |   internal transfer of   |
|                                                |         shares.          |
+-------------------------------------+----------+-------------+------------+
+-------------------------------------+----------+-------------+------------+



+----------------------------------------------------------------------------------+
|                                                                                  |
|8. Notified Details                                                               |
|                                                                                  |
+----------------------------------------------------------------------------------+
|A. Voting rights attached to shares                                               |
+--------------+-------------------+-----------------------------------------------+
|Class/type    |                   |                                               |
|of shares     |Situation previous |Resulting situation after the triggering       |
|              |to the Triggering  |transaction                                    |
|if possible   |transaction        |                                               |
|using the ISIN+---------+---------+----------+-------------------+----------------+
|CODE          |Number of|Number of|Number of |Number of Voting   |Percentage of   |
|              |Shares   |Voting   |Shares    |Rights             |voting rights   |
|              |         |Rights   |          |                   |                |
|              +---------+---------+----------+----------+--------+------+---------+
|              |         |         |          |Direct    |Indirect|Direct|Indirect |
+--------------+---------+---------+----------+----------+--------+------+---------+
|Ordinary      |         |         |          |          |        |      |         |
|Shares        |         |         |          |          |        |      |         |
|Sedol:        |         |         |          |          |        |      |         |
|0838182       |         |         |          |          |        |      |         |
+--------------+---------+---------+----------+----------+--------+------+---------+
|              |         |         |          |          |        |      |         |
+--------------+---------+---------+----------+----------+--------+------+---------+
|Holder 1:     |7,031,279|7,031,279|10,992,336|10,992,336|        |21.81%|         |
+--------------+---------+---------+----------+----------+--------+------+---------+
|Holder 2:     |2,700,517|2,700,517|NIL       |Nil       |        |0%    |         |
+--------------+---------+---------+----------+----------+--------+------+---------+
|Holder 3:     |2,135,950|2,135,950|NIL       |NIL       |        |0%    |         |
+--------------+---------+---------+----------+----------+--------+------+---------+
|Holder 4:     |1,621,330|1,621,330|2,496,740 |2,496,740 |        |4.96% |         |
+--------------+---------+---------+----------+----------+--------+------+---------+

+-------------------------------------------------------------------------------+
|B: Financial Instruments                                                       |
+-------------------------------------------------------------------------------+
|Resulting situation after the triggering transaction                           |
+---------------+-------------+-----------------+----------------+--------------+
|Type of        |Expiration   |Exercise/        |No. of voting   |Percentage of |
|financial      |date         |conversion period|rights that may |voting rights |
|instrument     |             |/date            |be acquired (if |              |
|               |             |                 |the instrument  |              |
|               |             |                 |is exercised/   |              |
|               |             |                 |converted)      |              |
+---------------+-------------+-----------------+----------------+--------------+
|               |             |                 |                |              |
+---------------+-------------+-----------------+----------------+--------------+

+------------------------------------------------------------------------------+
|Total (A+B)                                                                   |
+--------------------------------------+---------------------------------------+
|Number of voting rights               |Percentage of voting rights            |
+--------------------------------------+---------------------------------------+
|              13,489,076              |26.76%                                 |
+--------------------------------------+---------------------------------------+

+-------------------------------------------------------------------------+
|                                                                         |
|                                                                         |
| 9. Chain of controlled undertakings through which the voting rights and/|
|    or the financial instruments are effectively held, if applicable:    |
|                                                                         |
|                                                                         |
+-------------------------------------------------------------------------+
|Not Applicable                                                           |
+-------------------------------------------------------------------------+

+--------------------------------------------------------------------------+
|                                                                          |
|Proxy Voting:                                                             |
|                                                                          |
+----------------------------------------+---------------------------------+
|10. Name of the proxy holder:           |Not Applicable                   |
+----------------------------------------+---------------------------------+
|11. Number of voting rights proxy holder|Not Applicable                   |
|will cease to hold:                     |                                 |
+----------------------------------------+---------------------------------+
|12. Date on which proxy holder will     |Not Applicable                   |
|cease to hold rights:                   |                                 |
+----------------------------------------+---------------------------------+
|13. Additional information:             |North Atlantic Value LLP is the  |
|                                        |investment manager/advisor in    |
|                                        |respect of the full holding of   |
|                                        |26.76% as it is investment       |
|                                        |manager/adviser to holders 1, 2  |
|                                        |and 4 as well as the other       |
|                                        |clients included in holder 3.    |
+----------------------------------------+---------------------------------+
|14. Contact Name:                       |Kelly A. Winn, Bionostics PLC    |
+----------------------------------------+---------------------------------+
|15. Contact Telephone Number            |01993-885070                     |
+----------------------------------------+---------------------------------+

For notes on how to complete form TR-1 please see the FSA website.



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