RNS Number:8860P
Tissue Science Laboratories PLC
09 August 2005




9 August 2005

                              Tissue Science Laboratories plc

                       DISCLOSURE OF MATERIAL INTEREST IN SHARES

                              COMPANIES ACT 1985 (THE "ACT")

                                          SECTION 198

On Monday 8th August 2005, Tissue Science Laboratories plc (the "Company") had received notification relating to issued 
ordinary shares of 10p each in the capital of the Company (the "shares") and is given in fulfilment of the obligations 
imposed by sections 198 to 202 of the Companies Act 1985 (the "Act").

1.   Notification on behalf of Morley Fund Management Limited (a subsidiary of Aviva plc).

1.1  On behalf of Morley Fund Management Limited that immediately after the time when the obligation to make this 
     notification arose, Morley Fund Management Limited were interested in 3,276,134 shares.

1.2  The identity of the registered holders of the shares to which this notification relates and the number of 
     shares held by each of them are set out below.

2.   Notification on behalf of Aviva plc.

2.1  On behalf of Aviva plc that immediately after the time when the obligation to make this notification arose, 
     Aviva plc was interested in 3,276,134 shares, giving the Aviva group a total percentage interest in the shares of 
     11.24%.

2.2  The identity of the registered holders of the shares to which this notification relates and the number of 
     shares held by each of them are set out below.

Aviva's subsidiary Morley Fund Management Limited and thereby, Aviva plc, have advised that the registered holders and 
the respective numbers of shares held are as follows:

                                            Shares
BNY Norwich Union Nominees Ltd              184,066 ordinary shares
Chase GA Group Nominees Ltd                 170,464 ordinary shares
CUIM Nominee Ltd                            178,665 ordinary shares
Credit Agricole Indosuez                    300,000 ordinary shares
Vidacos Nominees Ltd                        2,442,939 ordinary shares
                                            ---------------------------
                                    Total   3,276,134 ordinary shares

END

Enquiries:

TSL plc                                          Tel:      01252 333 002
Martin Hunt, Chief Executive Officer

David Jennings, Finance Director
Hogarth Partnership Limited                      Tel:      020 7357 9477

Melanie Toyne Sewell / Kate Catchpole




                      This information is provided by RNS
            The company news service from the London Stock Exchange

END
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