TSL Thinksmart Limited

RNS Number:7604C
Tissue Science Laboratories PLC
21 October 2002

                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company

Tissue Science Laboratories PLC

2) Name of director

Martin Hunt

3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest



4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)



5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)



6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary



7) Number of shares/amount of
stock acquired



8) Percentage of issued class



9) Number of shares/amount
of stock disposed



10) Percentage of issued class



11) Class of security



12) Price per share



13) Date of transaction



14) Date company informed



15) Total holding following this notification



16) Total percentage holding of issued class following this notification



If a director has been granted options by the company please complete the
following boxes

17) Date of grant

21 October 2002

18) Period during which or date on which exercisable

Exercisable from 21 October 2005

19) Total amount paid (if any) for grant of the option

Nil

20) Description of shares or debentures involved: class, number

36,036 Ordinary 10p shares -

Tissue Science Laboratories PLC Executive Share Option Plan - 28,070

Tissue Science Laboratories PLC Sharesave Scheme - 7,966


21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise

93p

22) Total number of shares or debentures over which options held
following this notification

1,063,036

23) Any additional information



24) Name of contact and telephone number for queries

David Jennings 01252 333002

25) Name and signature of authorised company official responsible for
making this notification - David John Gregory Jennings - Company Secretary

Date of Notification....21 October 2002 ..............................


                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company

Tissue Science Laboratories PLC

2) Name of director

John Hamer

3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest



4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)



5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)



6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary



7) Number of shares/amount of
stock acquired



8) Percentage of issued class



9) Number of shares/amount
of stock disposed



10) Percentage of issued class



11) Class of security



12) Price per share



13) Date of transaction



14) Date company informed



15) Total holding following this notification



16) Total percentage holding of issued class following this notification



If a director has been granted options by the company please complete the
following boxes

17) Date of grant

21 October 2002

18) Period during which or date on which exercisable

Exercisable from 21 October 2005

19) Total amount paid (if any) for grant of the option

Nil

20) Description of shares or debentures involved: class, number

27,399 Ordinary 10p shares -

Tissue Science Laboratories PLC Executive Share Option Plan - 19,433

Tissue Science Laboratories PLC Sharesave Scheme - 7,966

21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise

93p

22) Total number of shares or debentures over which options held
following this notification

203,399

23) Any additional information



24) Name of contact and telephone number for queries

David Jennings 01252 333002

25) Name and signature of authorised company official responsible for
making this notification - David John Gregory Jennings - Company Secretary

Date of Notification....21 October 2002 ..............................

                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company

Tissue Science Laboratories PLC

2) Name of director

David John Gregory Jennings

3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest



4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)



5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)



6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary



7) Number of shares/amount of
stock acquired



8) Percentage of issued class



9) Number of shares/amount
of stock disposed



10) Percentage of issued class



11) Class of security



12) Price per share



13) Date of transaction



14) Date company informed



15) Total holding following this notification



16) Total percentage holding of issued class following this notification



If a director has been granted options by the company please complete the
following boxes

17) Date of grant

21 October 2002

18) Period during which or date on which exercisable

Exercisable from 21 October 2005

19) Total amount paid (if any) for grant of the option

Nil

20) Description of shares or debentures involved: class,

19,911 Ordinary 10p shares -

Tissue Science Laboratories plc Executive Share Option Plan 15,115

Tissue Science Laboratories plc Sharesave Scheme - 4,796

21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise

93p

22) Total number of shares or debentures over which options held
following this notification

121,911

23) Any additional information



24) Name of contact and telephone number for queries

David Jennings 01252 333002

25) Name and signature of authorised company official responsible for
making this notification - David John Gregory Jennings - Company Secretary

Date of Notification..21 October 2002................................


                      This information is provided by RNS
            The company news service from the London Stock Exchange
END

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