DARXX Dreyfus Treasury Prime Cash Mgmt Administrative Shs (MM)

000 A000000 07/31/2012
000 C000000 0000843781
000 D000000 N
000 E000000 NF
000 F000000 Y
000 G000000 N
000 H000000 N
000 I000000 6.1
000 J000000 U
001 A000000 DREYFUS TREASURY PRIME CASH MANAGEMENT
001 B000000 811-5718
001 C000000 2129226837
002 A000000 200 PARK AVENUE
002 B000000 NEW YORK
002 C000000 NY
002 D010000 10166
002 D020000 0144
003 000000 N
004 000000 N
005 000000 N
006 000000 N
007 A000000 N
007 B000000 0
008 A000001 THE DREYFUS CORPORATION
008 B000001 A
008 C000001 801-8147
008 D010001 NEW YORK
008 D020001 NY
008 D030001 10166
011 A000001 MBSC SECURITIES CORPORATION
011 B000001 8-13801
011 C010001 NEW YORK
011 C020001 NY
011 C030001 10166
012 A000001 DREYFUS TRANSFER, INC.
012 B000001 85-11312
012 C010001 NEW YORK
012 C020001 NY
012 C030001 10166
013 A000001 ERNST & YOUNG LLP
013 B010001 NEW YORK
013 B020001 NY
013 B030001 10036
014 A000001 BNY MELLON CAPITAL MARKETS, LLC
014 B000001 8-35255
014 A000002 CONVERGEX EXECUTION SOLUTIONS, LLC
014 B000002 8-46838
014 A000003 CONVERGEX PRIME SERVICES
014 B000003 8-67289
014 A000004 EZE CASTLE TRANSACTION SERVICES LLC
014 B000004 8-66577

014 A000005 G-TRADE SERVICES LLC
014 B000005 8-67304
014 A000006 MBSC SECURITIES CORPORATION
014 B000006 8-13801
014 A000007 PERSHING ADVISOR SOLUTIONS LLC
014 B000007 8-47425
014 A000008 PERSHING LLC
014 B000008 8-17574
014 A000009 WESTMINSTER RESEARCH ASSOCIATES LLC
014 B000009 8-28900
015 A000001 THE BANK OF NEW YORK MELLON
015 B000001 C
015 C010001 NEW YORK
015 C020001 NY
015 C030001 10286
015 E030001 X
018 000000 Y
019 A000000 Y
019 B000000 156
019 C000000 DREYFUSFAM
020 C000001 0
020 C000002 0
020 C000003 0
020 C000004 0
020 C000005 0
020 C000006 0
020 C000007 0
020 C000008 0
020 C000009 0
020 C000010 0
021 000000 0
022 A000001 BARCLAYS CAPITAL INC.
022 B000001 06-1031656
022 C000001 15071776
022 D000001 10466481
022 A000002 GOLDMAN, SACHS & CO.
022 B000002 13-5108880
022 C000002 8206443
022 D000002 5588708
022 A000003 DAIWA SECURITIES AMERICA INC.
022 B000003 13-5680329
022 C000003 11379704
022 D000003 199977
022 A000004 UBS SECURITIES LLC
022 B000004 13-3873456
022 C000004 6061033
022 D000004 99995
022 A000005 DEUTSCHE BANK SECURITIES INC.
022 B000005 13-2730828
022 C000005 5535071
022 D000005 0

022 A000006 CITIGROUP INC.
022 B000006 52-1568099
022 C000006 5015387
022 D000006 219967
022 A000007 COWEN & COMPANY, LLC
022 B000007 38-3698933
022 C000007 3840796
022 D000007 0
022 A000008 CREDIT AGRICOLE CHEUVREUX NORTH AMERICA, INC.
022 B000008 13-3867844
022 C000008 3133060
022 D000008 0
022 A000009 MORGAN STANLEY
022 B000009 36-3145972
022 C000009 2768025
022 D000009 0
022 A000010 MIZUHO SECURITIES USA INC.
022 B000010 36-2880742
022 C000010 2749376
022 D000010 0
023 C000000 77567299
023 D000000 17432119
024 000000 N
026 A000000 N
026 B000000 N
026 C000000 N
026 D000000 Y
026 E000000 N
026 F000000 N
026 G010000 N
026 G020000 N
026 H000000 Y
027 000000 Y
028 A010000 5848187
028 A020000 0
028 A030000 0
028 A040000 6352362
028 B010000 6915694
028 B020000 0
028 B030000 0
028 B040000 6909958
028 C010000 6444004
028 C020000 0
028 C030000 0
028 C040000 6690831
028 D010000 7357975
028 D020000 0
028 D030000 0
028 D040000 6696667
028 E010000 7518404
028 E020000 0

028 E030000 0
028 E040000 6592519
028 F010000 8272088
028 F020000 1
028 F030000 0
028 F040000 6444513
028 G010000 42356352
028 G020000 1
028 G030000 0
028 G040000 39686850
028 H000000 0
029 000000 N
030 A000000 0
030 B000000 0.00
030 C000000 0.00
031 A000000 0
031 B000000 0
032 000000 0
033 000000 0
034 000000 N
035 000000 0
036 B000000 0
037 000000 N
038 000000 0
039 000000 N
040 000000 Y
041 000000 Y
042 A000000 0
042 B000000 0
042 C000000 100
042 D000000 0
042 E000000 0
042 F000000 0
042 G000000 0
042 H000000 0
043 000000 11313
044 000000 0
045 000000 Y
046 000000 N
047 000000 Y
048 000000 0.200
048 A010000 0
048 A020000 0.000
048 B010000 0
048 B020000 0.000
048 C010000 0
048 C020000 0.000
048 D010000 0
048 D020000 0.000
048 E010000 0
048 E020000 0.000

048 F010000 0
048 F020000 0.000
048 G010000 0
048 G020000 0.000
048 H010000 0
048 H020000 0.000
048 I010000 0
048 I020000 0.000
048 J010000 0
048 J020000 0.000
048 K010000 0
048 K020000 0.000
049 000000 N
050 000000 N
051 000000 N
052 000000 N
053 A000000 Y
053 B000000 Y
053 C000000 N
054 A000000 Y
054 B000000 Y
054 C000000 Y
054 D000000 N
054 E000000 N
054 F000000 N
054 G000000 Y
054 H000000 N
054 I000000 N
054 J000000 Y
054 K000000 N
054 L000000 Y
054 M000000 Y
054 N000000 N
054 O000000 Y
055 A000000 Y
055 B000000 N
056 000000 Y
057 000000 N
058 A000000 N
059 000000 Y
060 A000000 Y
060 B000000 Y
061 000000 10000000
062 A000000 Y
062 B000000 106.4
062 C000000 0.0
062 D000000 0.0
062 E000000 0.0
062 F000000 0.0
062 G000000 0.0
062 H000000 0.0

062 I000000 0.0
062 J000000 0.0
062 K000000 0.0
062 L000000 0.0
062 M000000 0.0
062 N000000 0.0
062 O000000 0.0
062 P000000 0.0
062 Q000000 0.0
062 R000000 0.0
063 A000000 43
063 B000000 0.0
064 A000000 N
064 B000000 N
066 A000000 N
067 000000 N
068 A000000 N
068 B000000 N
069 000000 N
070 A010000 N
070 A020000 N
070 B010000 N
070 B020000 N
070 C010000 N
070 C020000 N
070 D010000 N
070 D020000 N
070 E010000 N
070 E020000 N
070 F010000 N
070 F020000 N
070 G010000 N
070 G020000 N
070 H010000 N
070 H020000 N
070 I010000 N
070 I020000 N
070 J010000 Y
070 J020000 N
070 K010000 N
070 K020000 N
070 L010000 N
070 L020000 N
070 M010000 N
070 M020000 N
070 N010000 N
070 N020000 N
070 O010000 Y
070 O020000 N
070 P010000 Y
070 P020000 N

070 Q010000 N
070 Q020000 N
070 R010000 N
070 R020000 N
071 A000000 0
071 B000000 0
071 C000000 0
071 D000000 0
072 A000000 6
072 B000000 10119
072 C000000 0
072 D000000 0
072 E000000 0
072 F000000 26548
072 G000000 0
072 H000000 0
072 I000000 638
072 J000000 415
072 K000000 0
072 L000000 89
072 M000000 87
072 N000000 105
072 O000000 0
072 P000000 0
072 Q000000 0
072 R000000 11
072 S000000 26
072 T000000 11313
072 U000000 0
072 V000000 0
072 W000000 187
072 X000000 39419
072 Y000000 29304
072 Z000000 4
072AA000000 53
072BB000000 31
072CC010000 0
072CC020000 0
072DD010000 3
072DD020000 1
072EE000000 0
073 A010000 0.0000
073 A020000 0.0000
073 B000000 0.0000
073 C000000 0.0000
074 A000000 0
074 B000000 0
074 C000000 31072261
074 D000000 0
074 E000000 0
074 F000000 0

074 G000000 0
074 H000000 0
074 I000000 0
074 J000000 0
074 K000000 0
074 L000000 35230
074 M000000 206
074 N000000 31107697
074 O000000 1899882
074 P000000 2309
074 Q000000 0
074 R010000 0
074 R020000 0
074 R030000 0
074 R040000 566
074 S000000 0
074 T000000 29204940
074 U010000 21235152
074 U020000 7970017
074 V010000 0.00
074 V020000 0.00
074 W000000 1.0000
074 X000000 20646
074 Y000000 0
075 A000000 26693649
075 B000000 0
076 000000 0.00
077 A000000 N
SIGNATURE JOHN B. HAMMALIAN
TITLE VICE PRESIDENT