AMSTERDAM—U.S. fertilizer maker CF Industries Holding Inc. on Thursday said it had reached an agreement to merge with parts of Netherlands-based OCI NV in a deal valued at $8 billion.

CF Industries said it would combine with OCI's European, North American and global distribution operations. The transaction is valued at $8 billion based on CF Industries current share price and includes $2 billion in debt.

Under the agreement, the companies will create a new holding company domiciled in the U.K. in which CF Industries shareholders will own a 72.3% stake. The remainder will be held by shareholders in OCI.

The companies said the deal will create the world's largest publicly-traded nitrogen company and comes amid a global takeover wave in the chemical sector.

Following the completion of the transaction, OCI's business will consist of a portfolio of industrial chemicals and nitrogen fertilizers. It will remain headquartered in the Netherlands and listed on the Euronext Amsterdam.

CF Industries and OCI on July 20 confirmed they were in talks following a report by the Wall Street Journal.

Write to Maarten van Tartwijk at maarten.vantartwijk@wsj.com

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