Adagene in Antibody Licensing Agreement With Sanofi
02 Marzo 2022 - 12:45PM
Dow Jones News
By Chris Wack
Adagene Inc. said it has entered into a collaboration and
exclusive license agreement with Sanofi to generate masked
monoclonal and bispecific antibodies for development and
commercialization by Sanofi.
Under the agreement, Adagene will be responsible for early stage
research activities to develop masked versions of Sanofi candidate
antibodies, using Adagene's SAFEbody technology.
Sanofi will be solely responsible for later stage research and
all clinical, product development and commercialization
activities.
Adagene said Sanofi will make an upfront payment of $17.5
million and will have the ability to advance two initial Sanofi
antibody candidates in the collaboration, followed by an option for
two additional candidates. Adagene will be eligible to receive
total potential development, regulatory and commercial milestone
payments of up to $2.5 billion for advancement of the candidates,
which will be exclusively developed and commercialized by Sanofi.
Adagene is eligible also to receive tiered royalties on global net
sales of approved collaboration products.
SAFEbody technology was designed by Adagene to address safety
and tolerability challenges associated with many antibody
therapeutics by using precision masking technology to shield the
binding domain of the biologic therapy.
Write to Chris Wack at chris.wack@wsj.com
(END) Dow Jones Newswires
March 02, 2022 06:30 ET (11:30 GMT)
Copyright (c) 2022 Dow Jones & Company, Inc.
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