First-Half Sales Performance in Line with
Full-Year 2024 Guidance
- Total revenues of
€70.8 million, including product sales of €68.3 million, in
line with anticipated supply and sales phasing
- Net Profit of €34.0 million,
including proceeds from PRV sale
- Operating profit of €46.7 million
compared to an operating loss of €35.0 million in the first half of
2023
- Cash position of €131.4
million
- Substantially
lower cash burn expected in the second half of 2024 as Valneva
completed its cost contributions to the agreed R&D budget for
its partnered Lyme disease program in the second quarter
- Significantly extended cash runway
with update of debt financing agreement1
Full-year 2024 Financial Guidance
Confirmed
- Expected total revenues between
€170 million and €190 million, including €160 million to
€180 million of product sales
- Expected R&D investments
between €60 million and €75 million
- Expected Other income between €100
million and €110 million, including €95 million from the PRV
sale
Strategic Pipeline Expansion, Strong
Clinical and Regulatory Execution
- Exclusive
worldwide license for S4V Shigella vaccine candidate, adding an
attractive Phase 2 clinical asset to Valneva’s R&D pipeline
without impacting full-year or mid-term financial guidance2
- Additional marketing authorizations
for single-shot IXCHIQ® granted in Europe and Canada ahead of
initial guidance; Ongoing regulatory reviews in the UK and Brazil;
Recommended by ACIP and adopted by U.S. CDC3
- New CEPI grant4 of $41.3 million
contributes significantly to Phase 4 costs and other studies
supporting broader access to the world’s first chikungunya
vaccine
- Reported positive six-month data
for Phase 3 adolescent study of IXCHIQ®5; expects to submit label
extensions for 12 to 17 years old in the U.S., Europe and Canada in
the second half of 2024
- IXCHIQ® two-year antibody
persistence data published in the Lancet Infectious Diseases
- IXCHIQ® pediatric Phase 2 study
fully enrolled
- Completed primary vaccinations
(three doses) of VALOR Lyme disease Phase 3 trial
participants6
- Initiated Phase 1 clinical trial
for second-generation Zika vaccine candidate7
Financial Information(Unaudited
results, consolidated per IFRS)
€ in million |
6 months ended June 30, |
|
2024 |
2023 |
Total revenues |
70.8 |
73.7 |
Product sales |
68.3 |
69.7 |
Net profit / loss |
34.0 |
(35.0) |
Adjusted EBITDA8 |
56.2 |
(28.3) |
Cash |
131.4 |
204.4 |
Saint-Herblain (France), August 13,
2024 – Valneva SE (Nasdaq: VALN; Euronext Paris: VLA), a
specialty vaccine company, today reported its consolidated
financial results for the first half of the year, ended June 30,
2024. The half year financial report, including the condensed
consolidated interim financial report and the half year management
report, is available on the Company’s website (Financial Reports –
Valneva).
Valneva will provide a live webcast beginning at
3 p.m. CEST / 9 a.m. EDT today. This webcast will also be available
on the Company’s website. Please refer to this link:
https://edge.media-server.com/mmc/p/mmuf83o5
Peter Bühler, Valneva’s Chief Financial
Officer, commented, “Our first half sales performance is
in line with our expectations. We aim to further capitalize on the
travel industry recovery as we focus on ramping up sales for
IXCHIQ® to support our commercial growth, while continuing to
execute on our key R&D and regulatory milestones. The
successful sale of our PRV and deferral of our loan reimbursement
allow us to maintain a solid cash position and, with completion of
our payments for the Lyme disease program in the second quarter, we
anticipate a significantly lower cash burn in
2024.”Commercial Portfolio
Valneva’s commercial portfolio is composed of
three travel vaccines, IXIARO®/JESPECT®, DUKORAL® and recently
launched IXCHIQ®. The Company also distributes certain third-party
products in countries where it operates its own marketing and sales
infrastructure.
Valneva’s sales in the first half of 2024 were
€68.3 million compared to €69.7 million (€64.0 million
excluding final COVID-19 vaccine sales) in the first half of 2023.
While product sales grew meaningfully in the second quarter and
included first sales for IXCHIQ®, first half 2024 sales were
affected by previously reported supply constraints for IXIARO® and
third-party products.
JAPANESE ENCEPHALITIS VACCINE
IXIARO®/JESPECT®
In the first half of 2024, IXIARO®/JESPECT®
sales increased by 38% to €41.9 million compared to €30.3 million
in the first half of 2023. The increase primarily reflects sales to
the U.S. military, which were minimal in the first half of 2023, as
well as increased sales to travelers.
CHOLERA / ETEC9-DIARRHEA VACCINE
DUKORAL®
In the first half of 2024, DUKORAL® sales were
€14.9 million compared to €17.1 million in the first half of
2023. The decrease was due to reduced marketing investments while
Valneva’s new manufacturing site in Sweden underwent regulatory
evaluation and approval.
CHIKUNGUNYA VACCINE
IXCHIQ®
IXCHIQ® is the world’s first and only licensed
chikungunya vaccine available to address this significant unmet
medical need. The vaccine is now approved in the U.S. 10, Europe11,
and Canada12 for the prevention of disease caused by the
chikungunya virus in individuals 18 years of age and older. The
U.S. launch is underway while first sales in Canada and Europe are
anticipated in the fourth quarter of 2024.
Following adoption of the U.S. Advisory
Committee on Immunization Practices (ACIP)’s recommendations by the
U.S. Centers for Disease Control and Prevention (CDC)13 at the
beginning of March 2024, Valneva recognized initial sales of €1.0
million in the first half of 2024. Key launch metrics, including
stocking and re-stocking across all sales channels, active customer
accounts, as well as reimbursement for IXCHIQ® by commercial and
MediCare insurance plans continue to track in line with
expectations.
In addition to ramping up sales, Valneva is
focusing on expanding the vaccine’s label and access. The Company
expects marketing authorizations in the UK and Brazil in the second
half of 2024 and recently expanded its partnership with CEPI14 to
support broader access to the vaccine in Low Middle-Income
Countries (LMICs), post-marketing trials and potential label
extensions in children, adolescents and pregnant women. CEPI will
provide Valneva up to $41.3 million of additional funding over the
next five years, with support from the European Union’s (EU)
Horizon Europe program.
Based on positive pivotal six-month Phase 3 data
reported in May 202415, Valneva expects to file for potential label
extensions for use in adolescents aged 12 to 17 years in the second
half of 2024. These data show that a single-dose vaccination with
IXCHIQ® induces a high and sustained immune response in 99.1% of
adolescents, and that the vaccine was generally well tolerated.
Conducted in Brazil in collaboration with Instituto Butantan, the
trial is also expected to support licensure of the vaccine in
Brazil, which would be the first potential approval for use in
endemic populations.
Additionally, Valneva recently completed
enrollment of a Phase 2 pediatric trial, VLA1553-221, in children
aged 1 to 11 years16, designed to support a Phase 3 pivotal
pediatric study and potential future label extension to this age
group.
The peer-reviewed medical journal, The Lancet
Infectious Diseases, also just published the vaccine’s Phase 3
antibody persistence results two years after vaccination with a
single dose. The data show that IXCHIQ®’s robust immune response
was sustained for two years by 97% of participants and was equally
durable in younger and older adults17. These data, which further
support the anticipated long-term durability of the immune
response, will also be used to potentially expand the vaccine’s
current label. Valneva will continue to measure antibody
persistence for a period of at least five years and expects to
report three-year durability results later this year.
THIRD-PARTY
DISTRIBUTION
Valneva distributes certain third-party vaccines
in countries where it operates its own marketing and sales
infrastructure. During the first half of 2024, third-party sales
decreased by 37% to €10.5 million compared to €16.5 million in
the first half of 2023 as a result of anticipated supply
constraints.
Valneva expects third-party sales to gradually
wind down to less than 5% of overall product sales by 2026/2027,
allowing the Company to improve gross margins.
Clinical Vaccine Candidates
LYME DISEASE VACCINE CANDIDATE –
VLA15 Phase 3 primary vaccination
completed
Valneva and Pfizer are developing VLA15, a Phase
3 vaccine candidate targeting Borrelia, the bacterium that causes
Lyme disease. VLA15 is the only Lyme disease program in late-stage
clinical development today and has received Fast Track designation
from the FDA. VLA15 is a multivalent recombinant protein vaccine
that targets six serotypes of Borrelia representing the most common
strains found in the United States and Europe.
Valneva and Pfizer reported results for the
Phase 2 clinical trials of VLA15 in both adult and pediatric
populations, in which high levels of antibodies against all six
serotypes were observed. Results of Phase 2 trials VLA15-201 and
VLA15-202 were published in the peer-reviewed medical journal, the
Lancet Infectious Diseases, in June 202418. Additional 18-month
booster results from Study VLA15-202 were also published in the
same journal in July 202419.
In July 2024, Valneva and Pfizer announced
completion of primary vaccinations (three doses) of over 9,000
participants in the Phase 3 trial “Vaccine Against Lyme for Outdoor
Recreationists” (VALOR)20.
Completion of the VALOR trial is still expected
by the end of 2025, with the aim for Pfizer to submit a Biologic
License Application (BLA) to the FDA and a Marketing Authorization
Application (MAA) to the EMA in 2026, subject to positive data.
Based on the agreement with Pfizer, Valneva’s
agreed-upon cost contributions for the Lyme disease program were
completed in the second quarter of 2024, contributing to a
substantially lower expected cash burn in the second half of
2024.
SHIGELLA VACCINE CANDIDATE –
S4V
Valneva recently entered into a strategic
partnership and exclusive licensing agreement with LimmaTech
Biologics AG for the development, manufacturing and
commercialization of Shigella4V (S4V), a tetravalent bioconjugate
vaccine candidate against shigellosis21.
Shigellosis, caused by Shigella bacteria, is the
second leading cause of fatal diarrheal disease worldwide. It is
estimated that up to 165 million cases of disease and an estimated
600,000 deaths are attributed to Shigella each year22, particularly
among children in Low- and Middle-Income Countries (LMICs). No
approved Shigella vaccine is currently available and the
development of Shigella vaccines has been identified as a priority
by the World Health Organization (WHO)23. Shigellosis also affects
international travelers from high-income countries and deployed
military personnel in endemic regions. The global market for a
vaccine against Shigella is estimated to exceed $500 million
annually24.
Under the terms of the agreement with Valneva,
LimmaTech will receive an upfront payment of €10 million and
be eligible to receive additional regulatory, development and
sales-based milestone payments of up to €40 million as well as low
double-digit royalties on sales. LimmaTech will conduct a Phase 2
Controlled Human Infection Model study (CHIM) in the U.S. and a
Phase 2 pediatric study in LMICs. Both clinical trials are expected
to begin in the second half of 2024. Valneva will assume all
further development, including CMC (chemistry, manufacturing and
controls) and regulatory activities, and be responsible for its
commercialization worldwide if approved.
The anticipated development path follows a
staggered and risk-mitigated strategy, allowing an efficient
capital allocation in line with Valneva’s communicated plan of
having a new R&D program in Phase 3 by 2027.
ZIKA VACCINE CANDIDATE –
VLA1601Phase 1 ongoing with second-generation
vaccine candidate
VLA1601 is a second-generation adjuvanted
inactivated vaccine candidate against the mosquito-borne disease
caused by the Zika virus (ZIKV). In March 2024, Valneva initiated a
Phase 1 clinical trial to investigate the safety and immunogenicity
of VLA160125. The randomized, placebo-controlled, Phase 1 trial,
VLA1601-102, is planned to enroll approximately 150 participants
aged 18 to 49 years in the United States. Participants will receive
a low, medium or high dose of VLA1601. In addition, the low dose of
VLA1601 will be evaluated with an additional adjuvant. Topline data
from the trial are expected in the first half of 2025.
Zika disease outbreaks have been reported in
tropical Africa, Southeast Asia, the Pacific Islands, and, since
2015, in the Americas. Zika virus transmission persists in several
countries in the Americas and in other endemic regions. To date, a
total of 89 countries and territories have reported evidence of
mosquito transmitted Zika virus infection26; however, surveillance
remains limited globally. There are no preventive vaccines or
effective treatments available and, as such, Zika remains a public
health threat and is included in the FDA’s Tropical Disease
Priority Review Voucher Program27.
A vaccine against ZIKV could be a valuable
addition to Valneva’s portfolio against mosquito-borne diseases,
which already includes IXCHIQ® and IXIARO®.
First Half 2024 Financial
Review (Unaudited, consolidated under IFRS)
RevenuesValneva’s total
revenues were €70.8 million in the six months ended June 30, 2024
compared to €73.7 million in the six months ended June 30, 2023.
Valneva’s total product sales reached €68.3 million in the six
months ended June 30, 2024 compared to €69.7 million in the same
period of 2023. The impact of currency fluctuations of €0.1 million
was minimal.Excluding final COVID-19 vaccine sales in the six
months ended June 30, 2023, travel vaccine sales show a growth of
€4.3 million or 7% year-over-year.IXIARO®/JESPECT® sales were €41.9
million in the six months ended June 30, 2024 compared to €30.3
million in the six months ended June 30, 2023. The 38% increase
primarily reflects sales to the U.S. military, which were minimal
in the first half of 2023, as well as increased sales to travelers.
The impact of foreign currency movements in IXIARO®/JESPECT® sales
was negligible.
DUKORAL® sales were €14.9 million in the six
months ended June 30, 2024 compared to €17.1 million in the
comparative period of 2023. This 13% decrease was due to reduced
marketing investments while Valneva’s new manufacturing site in
Sweden underwent regulatory evaluation and approval. Foreign
currency fluctuations had an immaterial impact on DUKORAL®
sales.Following adoption of the U.S. Advisory Committee on
Immunization Practices (ACIP)’s recommendations by the U.S. Centers
for Disease Control and Prevention (CDC) at the beginning of March
2024, Valneva recognized initial sales for IXCHIQ® of €1.0 million
in the first half of 2024.Third Party product sales were €10.5
million in the six months ended June 30, 2024 compared to €16.5
million in the six months ended June 30, 2023. This 37% decrease
was mainly driven by lower sales of Rabipur®/RabAvert® and
Encepur®, under the distribution agreement with Bavarian Nordic,
due to supply shortages. Other revenues, including revenues from
collaborations, licensing and services amounted to
€2.5 million in the six months ended June 30, 2024 compared to
€4.1 million in the same period of 2023. The reduction mainly
resulted from lower revenue recognition related to the R&D
collaboration activities for chikungunya with Instituto Butantan
and the divestment of the CTM unit in Sweden in July 2023.
Operating Result and adjusted
EBITDA Costs of goods and services sold (COGS) were €45.6
million in the six months ended June 30, 2024. The gross margin on
commercial product sales, excluding IXCHIQ®, amounted to 47.7%
compared to 40.0% in the six months ended June 30, 2023. COGS of
€17.8 million related to IXIARO® product sales, yielding a product
gross margin of 57.5%. COGS of €9.7 million related to DUKORAL®
product sales, yielding a product gross margin of 34.8%. Product
gross margins are expected to improve in the second half of the
year as the supply shortages during the first half have been
resolved. Of the remaining COGS in 2024, €7.7 million related to
the third-party products distribution business, €4.0 million to
IXCHIQ®, €2.1 million to idle capacity costs and €4.6 million to
cost of services. In 2023, overall COGS were €53.8 million, of
which €48.4 million related to cost of goods and €5.5 million
related to cost of services. Research and development expenses
amounted to €29.7 million in the six months ended June 30, 2024,
compared to €26.0 million in the six months ended June 30, 2023.
This increase was mainly driven by higher costs related to the
ongoing transfer of operations into the new Almeida manufacturing
facility and higher R&D costs for IXCHIQ®. Marketing and
distribution expenses in the first six months of 2024 amounted to
€23.2 million compared to €20.0 million in the first six months of
2023. The increase is mainly related to €9.8 million of expenses
associated with launch activities for IXCHIQ® (first half of 2023:
€7.8 million). In the six months ended June 30, 2024, general and
administrative expenses remained stable at €22.8 million after
€22.9 million in the same period of 2023. The largest expense
categories were employee-related expenses of €10.5 million and
consulting and other services of €9.6 million.During the first half
of 2024, a net gain of €90.8 million from the sale of the PRV was
recorded. The gross proceeds of $103 million were reduced by
transaction costs as well as contractual payment obligations
related to the sale of the PRV.Other income, net of other expenses
decreased to €6.4 million in the six months ended June 30, 2024
from €14.0 million in the six months ended June 30, 2023. In the
first half of 2023, Valneva recorded income from grants and tax
credits for research and development totaling €14.9 million, of
which €8.7 million were awarded by Scottish Enterprise (SE) for
non-COVID-19 vaccine development (IXCHIQ® and IXIARO®).Valneva
recorded an operating income of €46.7 million in the six months
ended June 30, 2024 compared to an operating loss of €35.0 million
in the comparative period of 2023. The increase was mainly the
result of the PRV sale.Adjusted EBITDA (as defined below) profit in
the six months ended June 30, 2024 was €56.2 million, whereas in
the six months ended June 30, 2023 an adjusted EBITDA loss of €28.3
million was recorded.
Net Result In the six months
ended June 30, 2024, Valneva generated a net profit of €34.0
million, mainly resulting from the sale of the PRV in February
2024. This compared to a net loss of €35.0 million in the first
half of 2023.Finance expense and currency effects in the first half
of 2024 resulted in a net finance expense of €12.8 million,
compared to a net finance expense of €3.9 million in the first half
of 2023. This increase was mainly due to €5.7 million higher
interest expenses on loans resulting from the amendment of the
Deerfield Management Company and OrbiMed (D&O) loan facility.
Additionally foreign exchange losses of €1.7 million were recorded
in the first half of 2024 compared to gains of €4.5 million
observed in the first half of 2023, primarily related to the
development of the USD and GBP exchange rates to the EUR.
Cash Flow and Liquidity Net
cash used in operating activities amounted to €66.3 million in the
six months ended June 30, 2024 compared to €65.4 million of cash
used in operating activities in the same period of 2023. Cash
outflows in the first half of 2024 were largely derived from the
operating loss for the period (net of gains from PRV sale)
amounting to €56.9 million and from working capital in the amount
of €31.2 million, which includes all payments to the Lyme disease
clinical program as per the R&D budget agreed between Pfizer
and Valneva. In 2023, changes in working capital were higher,
mainly related to higher payments to Pfizer in conjunction with the
Lyme disease program, reducing the refund liability. Cash inflows
from investing activities amounted to €87.6 million in the six
months ended June 30, 2024 compared to cash outflows of €6.6
million in the six months ended June 30, 2023. While both years
include outflows from construction activities across production
sites in Scotland and Sweden, the sale of the PRV positively
impacted 2024 by €90.8 million.Net cash used in financing
activities increased to €16.6 million in the six months ended June
30, 2024 from €9.5 million in the six months ended June 30, 2023.
This increase was primarily due to €5.4 million higher interest
payments resulting from the increase in the D&O loan facility.
Cash and cash equivalents were €131.4 million as at June 30,
2024, compared to €126.1 million at December 31, 2023.
Non-IFRS Financial Measures
Management uses and presents IFRS results as
well as the non-IFRS measure of Adjusted EBITDA to evaluate and
communicate its performance. While non-IFRS measures should not be
construed as alternatives to IFRS measures, management believes
non-IFRS measures are useful to further understand Valneva’s
current performance, performance trends, and financial condition.
Adjusted EBITDA is a common supplemental measure of performance
used by investors and financial analysts. Management believes this
measure provide additional analytical tools. Adjusted EBITDA is
defined as net profit / (loss) for the period before income tax,
finance income/expense, foreign exchange (gain)/loss, amortization,
depreciation, and impairment (excluding impairment loss of
disposal).
A reconciliation of Adjusted EBITDA to operating
loss, which is the most directly comparable IFRS measure, is set
forth below:
€ in million |
6 months ended June 30 |
(unaudited results, consolidated per IFRS) |
2024 |
2023 |
Net profit / (loss) |
34.0 |
(35.0) |
Add: |
|
|
Income tax benefit |
(0.2) |
(3.8) |
Total Finance income |
(0.8) |
(0.5) |
Total Finance expense |
12.0 |
8.9 |
Foreign exchange (gain)/ loss – net |
1.7 |
(4.5) |
Amortization |
2.5 |
3.2 |
Depreciation |
7.0 |
5.4 |
Impairment, excluding impairment loss of disposal |
- |
(1.9) |
Adjusted EBITDA |
56.2 |
(28.3) |
About Valneva
We are a specialty vaccine company that
develops, manufactures, and commercializes prophylactic vaccines
for infectious diseases addressing unmet medical needs. We take a
highly specialized and targeted approach, applying our deep
expertise across multiple vaccine modalities, focused on providing
either first-, best- or only-in-class vaccine solutions.
We have a strong track record, having advanced
multiple vaccines from early R&D to approvals, and currently
market three proprietary travel vaccines, including the world’s
first and only chikungunya vaccine, as well as certain third-party
vaccines.
Revenues from our growing commercial business
help fuel the continued advancement of our vaccine pipeline. This
includes the only Lyme disease vaccine candidate in advanced
clinical development, which is partnered with Pfizer, the world’s
most clinically advanced Shigella vaccine candidate, as well as
vaccine candidates against the Zika virus and other global public
health threats. More information is available at
www.valneva.com.
Valneva Investor and Media ContactsLaetitia
Bachelot-FontaineVP, Global Communications and European Investor
RelationsM +33 (0)6 4516 7099Laetitia.bachelotfontaine@valneva.com
|
Joshua Drumm, Ph.D.VP, Global Investor Relations M +001 917 815
4520joshua.drumm@valneva.com |
|
|
Forward-Looking StatementsThis
press release contains certain forward-looking statements relating
to the business of Valneva, including with respect to guidance for
certain financial results in fiscal year 2024 and mid-term outlook
on financial results, cash position, and other business
developments, including results of ongoing clinical trials, the
timing and possible occurrence of further or initial regulatory
approvals of its product candidates, the anticipated size of
markets for approved products and sales of those products, receipt
of funding from external sources, supply of products sold by
Valneva, and relationships with current business partners. In
addition, even if the actual results or development of Valneva are
consistent with the forward-looking statements contained in this
press release, those results or developments of Valneva may not be
indicative of future results. In some cases, you can identify
forward-looking statements by words such as "could," "should,"
"may," "expects," "anticipates," "believes," "intends,"
"estimates," "aims," "targets," or similar words. These
forward-looking statements are based on the current expectations of
Valneva as of the date of this press release and are subject to a
number of known and unknown risks and uncertainties and other
factors that may cause actual results, performance or achievements
to be materially different from any future results, performance or
achievement expressed or implied by these forward-looking
statements. These risks and uncertainties include those developed
or identified in any public documents filed with the French
financial markets authority (Autorité des marchés financiers) and
the U.S. Securities and Exchange Commission made or to be made by
Valneva. In particular, the expectations of Valneva could be
affected by, among other things, uncertainties involved in the
development and manufacture of vaccines (including in relation to
organic or strategic expansion of Valneva’s clinical pipeline),
unexpected clinical trial results, unexpected regulatory actions or
delays, competition in general, currency fluctuations, the impact
of the global and European financial crisis and other global
economic or political events, the ability to obtain or maintain
patent or other proprietary intellectual property protection, the
cancellation of existing contracts, the impact of a pandemic, and
changes in the regulatory environment in which Valneva operates.
The occurrence of any of these risks and uncertainties could
substantially harm Valneva’s business, financial condition,
prospects and results of operations. In light of these risks and
uncertainties, there can be no assurance that the forward-looking
statements made during this presentation will in fact be realized.
Valneva is providing the information in this press release as of
the date hereof and disclaims any intention or obligation to
publicly update or revise any forward-looking statements, whether
as a result of new information, future events, or otherwise.
1 Valneva Announces Extension of the Interest-Only Period of Its
Debt Facility with Deerfield and OrbiMed - Valneva2 Valneva and
LimmaTech Enter into a Strategic Partnership to Accelerate the
Development of the World’s Most Clinically Advanced Tetravalent
Shigella Vaccine Candidate - Valneva3 ACIP Vaccine Recommendations
and Schedules | CDC4 CEPI Expands Partnership with Valneva with a
$41.3 Million Grant to Support Broader Access to the World’s First
Chikungunya Vaccine - Valneva5 Valneva Reports Further Positive
Pivotal Phase 3 Data in Adolescents for its Single-Shot Chikungunya
Vaccine - Valneva6 Phase 3 VALOR Lyme Disease Trial: Valneva and
Pfizer Announce Primary Vaccination Series Completion - Valneva7
Valneva Initiates Phase 1 Trial of Second-Generation Zika Vaccine
Candidate - Valneva8 For additional information on Adjusted EBITDA,
please refer to the “Non-IFRS Financial Measures” section at the
end of the PR9 Indications differ by country - Please refer to
Product / Prescribing Information (PI) / Medication Guide approved
in your respective countries for complete information, incl.
dosing, safety and age groups in which this vaccine is licensed,
ETEC = Enterotoxigenic Escherichia coli (E. Coli) bacterium.10
Valneva Announces U.S. FDA Approval of World’s First Chikungunya
Vaccine, IXCHIQ® - Valneva11 Valneva Receives Marketing
Authorization in Europe for the World’s First Chikungunya Vaccine,
IXCHIQ® - Valneva12 Valneva Announces Health Canada Approval of the
World’s First Chikungunya Vaccine, IXCHIQ® - Valneva13 ACIP Vaccine
Recommendations and Schedules | CDC14 CEPI Expands Partnership with
Valneva with a $41.3 Million Grant to Support Broader Access to the
World’s First Chikungunya Vaccine - Valneva15 Valneva Reports
Further Positive Pivotal Phase 3 Data in Adolescents for its
Single-Shot Chikungunya Vaccine - Valneva16 Valneva Vaccinates
First Participant in Pediatric Trial of Single-Shot Chikungunya
Vaccine - Valneva17
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(24)00357-8/fulltext
18 Valneva Announces Publication of Lyme Disease Phase 2 Trials in
the Lancet Infectious Diseases - Valneva19 Immunogenicity and
safety of an 18-month booster dose of the VLA15 Lyme borreliosis
vaccine candidate after primary immunisation in healthy adults in
the USA: results of the booster phase of a randomised, controlled,
phase 2 trial - The Lancet Infectious Diseases20 Phase 3 VALOR Lyme
Disease Trial: Valneva and Pfizer Announce Primary Vaccination
Series Completion - Valneva21 LimmaTech Biologics AG22 Shigellosis
| CDC Yellow Book 202423 Immunization, Vaccines and Biologicals
(who.int)24 Valneva’s Initial internal assessment 25 Valneva
Initiates Phase 1 Trial of Second-Generation Zika Vaccine Candidate
- Valneva26 Zika virus disease (who.int)27 Tropical Disease
Priority Review Voucher Program | FDA
Full-year 2024 Financial Guidance Confirmed
- 2024_08_13_VLA_H1_Results_EN_Final
Grafico Azioni Valneva (EU:VLA)
Storico
Da Dic 2024 a Gen 2025
Grafico Azioni Valneva (EU:VLA)
Storico
Da Gen 2024 a Gen 2025