By Sara Sjolin, MarketWatch

LONDON (MarketWatch) -- U.K. stocks retreated from a 41/2 year high on Thursday, as shares of Vodafone Group PLC dropped on speculation the telecom firm is considering an acquisition, while weak euro-zone growth data spooked the broader market.

The FTSE 100 index dropped 0.5% to close at 6,327.36, retreating from its highest closing level since May 2008 reached on Wednesday.

Shares of Vodafone (VOD) dropped 2.4%, adding to the previous day's losses when reports said the wireless-telecom firm was considering a takeover of German cable network operator Kabel Deutschland Holding AG . .

Shire PLC slumped 5.5%, as it reported a drop in fourth-quarter operating profit.

Shares of Barclays PLC (BCS) lost 2.2%, after Investec Securitites cut the bank to hold from buy.

"We believe that, for now, Barclays' shares have arrived. They have traveled 119% in less than 7 months since the July 2012 lows," said Ian Gordon, an analyst at Investec, in a note.

"Although we downgrade Barclays to an absolute hold today, we continue to expect it to deliver further relative outperformance. A long Barclays/short Royal Bank of Scotland trade has returned over 15% year-to-date, but we still see further value in such a position," he said.

News from the euro zone weighed on sentiment in London. Gross domestic product for the currency bloc fell 0.6% in the fourth quarter of last year, coming in below analysts' expectations.

Shares of Rio Tinto PLC (RIO) fell 0.3% after the miner swung to its first full-year loss, hurt by a sharp drop in commodity prices and an almost $14 billion impairment charge.

Most other mining firms were also under pressure, tracking most metals prices lower. Shares of Kazakhmys PLC lost 2%, while Antofagasta PLC slipped 0.5%.

Shares of cruise liner Carnival PLC (CCL) fell 2.9%, after it late Wednesday said that a fire on one of its cruise ships will shave off 8 cents to 10 cents of its earnings in the first half of 2013. A fire over the weekend left the Carnival Triumph ship adrift in the Gulf of Mexico with more than 4,000 people on board.

On an upbeat note in London, shares of fashion retailer Next PLC climbed 1.2%, after HSBC lifted the stock to overweight from neutral. The bank further raised its recommendation on online clothing retailer Asos PLC to overweight from neutral, sending its shares 1.5% higher.

Outside the main index in London, shares of soft-drinks firm Britvic PLC sank 7.1% after J.P. Morgan Cazenove cut the stock to underweight from neutral and Société Générale slashed its recommendation to sell from buy. On Wednesday, the U.K.'s Office of Fair Trading referred the proposed merger with A.G. Barr PLC to the Competition Commission for further investigation.

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