AMED Amedeo Res

RNS No 6302a
MERRILL LYNCH INTERNATIONAL
30 June 1999


                                                           FORM 38.5 (SUMMARY)
A M E N D M E N T                           

Lodge with Company Announcements Office and the Panel.  Use a separate form   
                        
for each class of securities in which dealings have been made.                
           


                       CONNECTED EXEMPT MARKET-MAKERS:                        
   
    DISCLOSURE UNDER RULE 38.5 OF THE CITY CODE ON TAKEOVERS AND MERGERS      
                     

Name of EMM               Merrill Lynch International               

Date of disclosure               June 30, 1999              

Contact name               Linda Blatt              

Telephone number               0171 772 1040               

Please see attached disclosure of dealings under Rule 38.5 in the securities  
of the following companies:                            

Chiroscience Group plc

Chiroscience Group plc


AMENDMENT                            

If the attached Rule 38.5 disclosure is to amend a previous disclosure, please
                           
state which element(s) of previous disclosure was incorrect:                  
         

Chiroscience Group Plc (28/06/99) amendment to shares bought
Chiroscience Group Plc (25/06/99) amendment to shares bought
           
In the case of option business or dealings in derivatives full details should 
                          
be given on a separate sheet so that the nature of the dealings can be fully  
                         
understood.  For options this should include the number of securities under   
                        
option, the exercise period (or in the case of exercise, the exercise date),  
                         
the exercise price and any option money paid or received.  For derivatives    
                       
this should include, at least, the number of reference securities to which    
                       
they relate (when relevant), the maturity date (or if applicable the closing  
                         
out date) and the reference price.                            

For full details of disclosure requirements see Rules 8 and 38 of the Code.   
                        
If in doubt contact the Monitoring Section of the Panel,                      
     
Tel. No: 0171 638 0129                            

                            
                            
AMENDMENT                            
                                                                     FORM 38.5
                           

                    CONNECTED EXEMPT MARKET-MAKERS:                     
      
     DISCLOSURE UNDER RULE 38.5 OF THE CITY CODE ON TAKEOVERS AND MERGERS     
                      
Dealing in                      Chiroscience Group plc              

Class of security               Ordinary              

Date of disclosure              30/6/1999              

Date of dealing                 28/6/1999              

Name of EMM                     Merrill Lynch International                   
        
Name of offeree/offeror with whom connected    Chiroscience Group plc

Total number of securities purchased                            547,484
                            
Highest price paid*                                             #3.11
                            
Lowest price paid*                                              #3.08
                            
Total number of securities sold                                 535,638
                            
Highest price received*                                         #3.13
                            
Lowest price received*                                          #3.11

*Currency must be stated                            
                            

                            
AMENDMENT                            
                                                                     FORM 38.5
                           
                          CONNECTED EXEMPT MARKET-MAKERS:                     
      
     DISCLOSURE UNDER RULE 38.5 OF THE CITY CODE ON TAKEOVERS AND MERGERS     
                      

Dealing in                      Chiroscience Group plc              

Class of security               Ordinary              

Date of disclosure              30/6/1999              

Date of dealing                 25/6/1999              

Name of EMM                     Merrill Lynch International                   
        
Name of offeree/offeror with whom connected      Chiroscience Group plc

Total number of securities purchased                            51,580
                            
Highest price paid*                                             #3.11
                            
Lowest price paid*                                              #3.10
                            
Total number of securities sold                                 1,530
                            
Highest price received*                                         #3.15
                            
Lowest price received*                                          #3.13



*Currency must be stated                            
                            
END

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