AMED Amedeo Res

RNS No 7410q
LEHMAN BROTHERS INTERNATIONAL (EUROPE)
1 July 1999



                                                            FORM 38.5

                                       
                        CONNECTED EXEMPT MARKET-MAKERS:
      DISCLOSURE UNDER RULE 38.5 OF THE CITY CODE ON TAKEOVERS AND MERGERS
                                       
                                       
                                       
Dealing in ..CHIROSCIENCE GROUP PLC......................... (name of company)

Class of security ..ORDINARY SHARES...........................................

Date of disclosure ...........................................................

Date of dealing ..28 JUNE 1999................................................

Name of EMM ..LEHMAN BROTHERS INTERNATIONAL (EUROPE)..........................

Name of offeree/offeror with whom connected ..CHIROSCIENCE GROUP PLC..........



Total number of securities purchased ..100,000........................

Highest price paid*            ........#3.11..........................

Lowest price paid*             ........#3.11..........................


Total number of securities sold .......100,000........................

Highest price received*         .......#3.11...........................

Lowest price received*          .......#3.11...........................


*Currency must be stated

                                                            FORM 38.5

                                       
                        CONNECTED EXEMPT MARKET-MAKERS:
      DISCLOSURE UNDER RULE 38.5 OF THE CITY CODE ON TAKEOVERS AND MERGERS
                                       
                                       
                                       
Dealing in ..CHIROSCIENCE GROUP PLC......................... (name of company)

Class of security ..ORDINARY SHARES...........................................

Date of disclosure ...........................................................

Date of dealing ..29 JUNE 1999................................................

Name of EMM ..LEHMAN BROTHERS INTERNATIONAL (EUROPE)..........................

Name of offeree/offeror with whom connected ..CHIROSCIENCE GROUP PLC..........



Total number of securities purchased ..137,090........................

Highest price paid*            ........#3.08..........................

Lowest price paid*             ........#3.08..........................


Total number of securities sold .......137,000........................

Highest price received*         .......#3.08 1/2.......................

Lowest price received*          .......#3.11...........................


*Currency must be stated


END


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