(1)
Consists of 8,748,629 Common Shares and 2,920,000 Common Share purchase warrants (“Warrants”) as reported in BVF Partners L.P.’s Form 13F filed with the SEC on November 14, 2023. The address for this entity is 44 Montgomery St., 40th Floor, San Francisco, CA 94104.
(2)
Consists of 7,898,583 Common Shares beneficially owned by Bellevue Group AG as reported in Bellevue Group AG’s Form 13F filed with the SEC on November 14, 2023. The address for Bellevue Group AG is Seestrasse 16, CH-8700 Küsnacht, Switzerland.
(3)
Consists of 4,287,094 Common Shares as reported in Soleus Capital Management, L.P. Form 13F filed with the SEC on November 14, 2023. The address for this entity is 104 Field Point Road, 2nd Floor, Greenwich, CT 06830.
(4)
Consists of 4,199,253 Common Shares as reported in PFM Health Sciences, LP’s (“PFM”) Form 13F filed with the SEC on November 14, 2023. The address for this entity is 475 Sansome Street, Suite 1720, San Francisco, California 94111.
(5)
Consists of 4,181,183 Common Shares beneficially owned by Morgan Stanley & Co as reported in Morgan Stanley & Co’s Form 13F filed with the SEC on November 15, 2023. The address for this entity is 1585 Broadway, New York, NY 10036.
(6)
Consists of (i) 65,765 Common Shares and (ii) 2,038,999 Common Shares pursuant to options exercisable within 60 days of the Record Date held by Dr. Parkinson.
(7)
Consists of (i) 14,022 Common Shares and (ii) 1,558,282 Common Shares pursuant to options exercisable within 60 days of the Record Date held by Mr. Virsik.
(8)
Consists of (i) 784,404 Common Shares and (ii) 63,793 Common Shares pursuant to options exercisable within 60 days of the Record Date held by Mr. Berger.
(9)
Consists of (i) 33,343 Common Shares and (ii) 631,250 Common Shares pursuant to options exercisable within 60 days of the Record Date held by Mr. Wood.
(10)
Consists of (i) 5,124 Common Shares and (ii) 555,938 Common Shares pursuant to options exercisable within 60 days of the Record Date held by Dr. Cesano.
(11)
Consists of (i) 47,950 Common Shares and (ii) 137,000 Common Shares pursuant to options exercisable within 60 days of the Record Date held by Dr. Glickman and (iii) 8,460 Common Shares indirectly held in the name of his spouse.
(12)
Consists of (i) 30,002 Common Shares and (ii) 106,000 Common Shares pursuant to options exercisable within 60 days of the Record Date held by Mr. Requadt.
(13)
Consists of 106,000 Common Shares pursuant to options exercisable within 60 days of the Record Date held by Mr. Sollis.
(14)
Consists of (i) 14,299 Common Shares and (ii) 89,000 Common Shares pursuant to options exercisable within 60 days of the Record Date held by Mr. Martin.
(15)
Consists of (i) 2,881 Common Shares and (ii) 89,000 Common Shares pursuant to options exercisable within 60 days of the Record Date held by Ms. Thorell.
(16)
Consists of 89,000 Common Shares pursuant to options exercisable within 60 days of the Record Date held by Mr. Zweifach.
(17)
Consists of 25,000 Common Shares pursuant to options exercisable within 60 days of the Record Date held by Dr. Kantoff.
(18)
Consists of 12,500 Common Shares pursuant to options exercisable within 60 days of the Record Date held by Ms. Merendino.