By Sara Sjolin, MarketWatch

LONDON (MarketWatch) -- U.K.'s FTSE index dropped on Wednesday, with mining firms leading the way south, as investors waited for the quarterly inflation report from the Bank of England and whether the central bank will reveal a framework for forward guidance.

The benchmark lost 0.5% to 6,573.93, building on a 0.2% loss from Tuesday.

The major focal point in London in Wednesday's trade was the first inflation report from the Bank of England with Governor Mark Carney at the helm. Market participants were eagerly awaiting news on if or how the central bank will deploy forward guidance.

"Carney is widely tipped to announce some form of forward guidance alongside the inflation report but what form this guidance takes remains uncertain," analysts at Deutsche Bank said in a note.

"DB expects 'loose-form' guidance from the bank, rather than an explicit time or data-based 'pre-commitment'. An example of something that they could say in a statement would be: 'The Bank intends to keep interest rates at their current level or below for a prolonged period (ECB-esque), and at least until the level of economic output has well surpassed its previous peak,'" they said.

The pound (GBPUSD) was also lower ahead of the report, trading at $1.5302.

Among notable movers on the stock markets, shares of TUI Travel PLC slid 5.1% after the travel agency reported an operating loss for the nine-month period to June 30.

Shares of Randgold Resources Ltd. (GOLD) shaved off 3.5% after the gold miner reported second-quarter profit below expectations. Other miners were also lower as most metals prices declined. Heavyweight Rio Tinto PLC (RIO) dropped 1.8% and BHP Billiton PLC (BHP) fell 0.8%.

On a more upbeat note, shares of Old Mutual PLC jumped 4.2% after the insurance firm reported a rise in first-half pretax profit and funds under management.

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