UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
Under the Securities Exchange Act of 1934
(Amendment No. 3)
NEUROGENE
inc. (f/k/a NEOLEUKIN THERAPEUTICS, INC.)
(Name of Issuer)
Common Stock, $0.000001 par value
(Title of Class of Securities)
64135M105
(CUSIP Number)
December 18, 2023
(Date of Event Which Requires Filing of this
Statement)
Check the appropriate box to designate the rule pursuant to which this
Schedule is filed:
¨ Rule
13d-1(b)
x Rule
13d-1(c)
¨ Rule
13d-1(d)
* The remainder of this cover page shall be filled
out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent
amendment containing information which would alter the disclosures provided in a prior cover page.
The information required in the remainder of this
cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”)
or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see
the Notes).
CUSIP
No. 64135M105
1 |
Name of Reporting Person
Redmile Group, LLC |
2 |
Check the Appropriate Box if
a Member of a Group (See Instructions)
(a)
¨
(b)
¨ |
3 |
SEC Use Only |
4 |
Citizenship or Place of Organization
Delaware |
number
of
shares
beneficially
owned by
each
reporting
person with
|
5 |
Sole Voting Power
0 |
6 |
Shared Voting Power
1,282,661 (1)
|
7 |
Sole
Dispositive Power
0 |
8 |
Shared Dispositive Power
1,282,661 (1)
|
9 |
Aggregate Amount Beneficially
Owned by Each Reporting Person
1,282,661 (1)
|
10 |
Check if the Aggregate Amount
in Row (9) Excludes Certain Shares (See Instructions)
|
11 |
Percent of Class Represented
by Amount in Row (9)
9.9% (2)
|
12 |
Type of Reporting Person (See
Instructions)
IA, OO |
(1) After giving effect to (i) the reverse merger that closed on December
18, 2023 by the Issuer (formerly Neoleukin Therapeutics, Inc.) and the pre-merger Neurogene Inc., which became a wholly owned subsidiary
of the Issuer (the “Merger”), and (ii) each of the 1-for-5 reverse stock split with respect to the Issuer’s Common Stock
that was effected on September 25, 2023 and the 1-for-4 reverse stock split with respect to the Issuer’s Common Stock that was effected
on December 18, 2023 immediately prior to the closing of the Merger (collectively, the “Reverse Stock Splits”), Redmile Group,
LLC’s beneficial ownership of the Issuer’s common stock (“Common Stock”) is comprised of 1,266,905 shares of Common
Stock owned by certain private investment vehicles and/or sub-advised accounts managed by Redmile Group, LLC (“Redmile”),
including Redmile Biopharma Investments I, L.P. Subject to the Beneficial Ownership Blocker (as defined below), Redmile may also be deemed
to beneficially own 103,407 shares of Common Stock issuable upon exercise of certain warrants to purchase Common Stock (the “Warrants”).
Pursuant to the terms of the Warrants, the Common Stock that may be acquired upon exercise of the Warrants shall be limited to the extent
that, following such exercise, the total number of shares of Common Stock then beneficially owned by the holder of the Warrants, together
with such holder’s affiliates and any other person whose beneficial ownership of Common Stock would be aggregated with such holder’s
for the purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), would exceed the
Beneficial Ownership Limitation (the “Beneficial Ownership Blocker”). The “Beneficial Ownership Limitation” is
9.99% of the shares of Common Stock then issued and outstanding, which percentage may be changed at a holder’s election upon 61
days’ notice to the Issuer. The Common Stock and the Warrants may be deemed beneficially owned by Redmile as investment manager
of such private investment vehicles and/or sub-advised accounts. The reported securities may also be deemed beneficially owned by Jeremy
C. Green as the principal of Redmile. Redmile and Mr. Green (collectively, the “Reporting Persons”) each disclaim beneficial
ownership of these shares, except to the extent of its or his pecuniary interest in such shares, if any.
(2) Percentage
based on: (i) 12,823,696 shares of Common Stock outstanding as of December 18, 2023, as reported by the Issuer in its Form 8-K filed
with SEC on December 18, 2023 (the "Form 8-K") plus (ii) 15,756 shares of Common Stock issuable upon exercise of certain of the
Warrants, which due to the Beneficial Ownership Limitation is the maximum number of shares that could be issued upon exercise of the
Warrants.
CUSIP
No. 64135M105
1 |
Name of Reporting Person
Jeremy C. Green |
2 |
Check the Appropriate Box if
a Member of a Group (See Instructions)
(a)
¨
(b)
¨ |
3 |
SEC Use Only |
4 |
Citizenship or Place of Organization
United Kingdom |
number
of
shares
beneficially
owned by
each
reporting
person with
|
5 |
Sole Voting Power
0 |
6 |
Shared Voting Power
1,282,661 (3)
|
7 |
Sole
Dispositive Power
0 |
8 |
Shared Dispositive Power
1,282,661 (3)
|
9 |
Aggregate Amount Beneficially
Owned by Each Reporting Person
1,282,661 (3)
|
10 |
Check if the Aggregate Amount
in Row (9) Excludes Certain Shares (See Instructions)
|
11 |
Percent of Class Represented
by Amount in Row (9)
9.9% (4)
|
12 |
Type of Reporting Person (See
Instructions)
IN, HC |
(3) After giving effect to the Merger and the Reverse Stock Splits, Jeremy
C. Green’s beneficial ownership of Common Stock is comprised of 1,266,905 shares of Common Stock owned by certain private investment
vehicles and/or sub-advised accounts managed by Redmile, including Redmile Biopharma Investments I, L.P. Subject to the Beneficial Ownership
Blocker, Mr. Green may also be deemed to beneficially own 103,407 shares of Common Stock issuable upon exercise of the Warrants. Pursuant
to the terms of the Warrants, the Common Stock that may be acquired upon exercise of the Warrants shall be limited to the extent that
the Beneficial Ownership Blocker applies. The Common Stock and the Warrants together may be deemed beneficially owned by Redmile as investment
manager of such private investment vehicles and/or sub-advised accounts. The reported securities may also be deemed beneficially owned
by Jeremy C. Green as the principal of Redmile. The Reporting Persons each disclaim beneficial ownership of these shares, except to the
extent of its or his pecuniary interest in such shares, if any.
(4) Percentage based on (i) 12,823,696 shares of Common Stock outstanding as of December 18, 2023, as reported by the Issuer in its Form 8-K, plus (ii) 15,756 shares of Common Stock issuable upon exercise of certain of the Warrants, which due to the Beneficial Ownership Limitation is the maximum number of shares that could be issued upon exercise of the Warrants.
CUSIP
No. 64135M105
1 |
Name of Reporting Person
Redmile Biopharma Investments I, L.P. |
2 |
Check the Appropriate Box if
a Member of a Group (See Instructions)
(a)
¨
(b)
¨ |
3 |
SEC Use Only |
4 |
Citizenship or Place of Organization
Delaware |
number
of
shares
beneficially
owned by
each
reporting
person with
|
5 |
Sole Voting Power
0 |
6 |
Shared Voting Power
652,030
|
7 |
Sole
Dispositive Power
0 |
8 |
Shared Dispositive Power
652,030
|
9 |
Aggregate Amount Beneficially
Owned by Each Reporting Person
652,030
|
10 |
Check if the Aggregate Amount
in Row (9) Excludes Certain Shares (See Instructions)
|
11 |
Percent of Class Represented
by Amount in Row (9)
5.1% (5)
|
12 |
Type of Reporting Person (See
Instructions)
PN |
(5) Percentage based on 12,823,696 shares of Common Stock outstanding as
of December 18, 2023, as reported by the Issuer in its Form 8-K.
The Reporting Persons initially reported their beneficial ownership
of the Issuer’s Common Stock on Schedule 13G on February 16, 2021, and subsequently amended as required. On July 27, 2023, the
Reporting Persons filed a Schedule 13D with respect to their beneficial ownership of Common Stock in accordance with Rule 13d-1(e) of
the Act following the execution by Redmile of an agreement with the Issuer to vote all of the shares of Common Stock held by the private
investment vehicles and sub-advised accounts managed by Redmile in favor of the Merger. The closing of the Merger occurred on December
18, 2023, at which time the Reporting Persons again became eligible to report their beneficial ownership of Common Stock on Schedule
13G pursuant to Rule 13d-1(h) of the Act.
Item 1.
(a) Name
of Issuer
Neurogene Inc.
(b) Address
of Issuer’s Principal Executive Offices
535 W 24th Street, 5th Floor
New York, New York 10011
Item 2.
(a) Names
of Persons Filing
Redmile Group, LLC
Jeremy C. Green
Redmile Biopharma Investments I, L.P.
(b) Address
of Principal Business office or, if None, Residence
Redmile Group, LLC
One Letterman Drive
Building D, Suite D3-300
The Presidio of San Francisco
San Francisco, California 94129
Jeremy C. Green
c/o Redmile Group, LLC (NY Office)
45 W. 27th Street, Floor 11
New York, NY 10001
Redmile Biopharma Investments I, L.P.
c/o Redmile Group, LLC
One Letterman Drive
Building D, Suite D3-300
The Presidio of San Francisco
San Francisco, California 94129
(c) Citizenship
Redmile Group, LLC: Delaware
Jeremy C. Green: United Kingdom
Redmile Biopharma Investments I, L.P.: Delaware
(d) Title of
Class of Securities
Common Stock, $0.000001 par value
(e) CUSIP Number
64135M105 *
|
* |
On September
25, 2023 the Common Stock of the Issuer commenced trading under the CUSIP number 64049K203 and the Issuer effected a 1-for-5 reverse split
with respect to its Common Stock. On December 18, 2023, following the Merger and a 1-for-4 reverse stock split with respect to the Issuer’s
Common Stock, the Common Stock commenced trading under the name Neurogene Inc. (Nasdaq: NGNE) with a CUSIP number of 64135M105. |
Item 3. | If
this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or
(c), check whether the person filing is a: |
| (a) | ¨ Broker
or dealer registered under section 15 of the Act (15 U.S.C. 78o); |
| (b) | ¨ Bank
as defined in section 3(a)(6) of the Act (15 U.S.C. 78c); |
| (c) | ¨ Insurance
company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c); |
| (d) | ¨ Investment
company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C 80a-8); |
| (e) | ¨ An
investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E); |
| (f) | ¨ An
employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F); |
| (g) | ¨ A
parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G); |
| (h) | ¨ A
savings associations as defined in Section 3(b) of the Federal Deposit Insurance
Act (12 U.S.C. 1813); |
| (i) | ¨ A
church plan that is excluded from the definition of an investment company under section 3(c)(14)
of the Investment Company Act of 1940 (15 U.S.C. 80a-3); |
| (j) | ¨ A
non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J); |
| (k) | ¨ Group,
in accordance with § 240.13d-1(b)(1)(ii)(K). If filing as a non-U.S. institution in
accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution: __________ |
(a) Amount beneficially
owned:
Redmile Group, LLC – 1,282,661 *
Jeremy C. Green – 1,282,661 *
Redmile Biopharma Investments I, L.P. – 652,030
(b) Percent of
class:
Redmile Group, LLC – 9.9%**
Jeremy C. Green – 9.9%**
Redmile Biopharma Investments I, L.P. – 5.1%***
(c) Number of
shares as to which Redmile Group, LLC has:
| (i) | Sole power to vote or to direct the vote: |
| | 0 |
| (ii) | Shared power to vote or to direct the vote: |
| | 1,282,661 * |
| (iii) | Sole power to dispose or to direct the disposition of: |
| | 0 |
| (iv) | Shared power to dispose or to direct the disposition of: |
| | 1,282,661 * |
Number of shares as to which Jeremy C. Green has:
| (i) | Sole power to vote or to direct the vote: |
| | 0 |
| (ii) | Shared power to vote or to direct the vote: |
| | 1,282,661 * |
| (iii) | Sole power to dispose or to direct the disposition of: |
| | 0 |
| (iv) | Shared power to dispose or to direct the disposition of: |
| | 1,282,661 * |
Number of shares as to which Redmile Biopharma Investments
I, L.P. has:
| (i) | Sole power to vote or to direct the vote: |
| | 0 |
| (ii) | Shared power to vote or to direct the vote: |
| | 652,030 |
| (iii) | Sole power to dispose or to direct the disposition of: |
| | 0 |
| (iv) | Shared power to dispose or to direct the disposition of: |
| | 652,030 |
| * | After giving effect to the Merger and the Reverse Stock Splits, Redmile’s and Jeremy C. Green’s
beneficial ownership of the Issuer’s Common Stock is comprised of 1,266,905 shares of Common Stock owned by certain private investment
vehicles and/or sub-advised accounts managed by Redmile, including Redmile Biopharma Investments I, L.P. Subject to the Beneficial Ownership
Blocker, Redmile and Mr. Green may also be deemed to beneficially own 103,407 shares of Common Stock issuable upon exercise of the Warrants.
Pursuant to the terms of the Warrants, the Common Stock that may be acquired upon exercise of the Warrants shall be limited to the extent
that the holder of the Warrants, together with such holder’s affiliates and any other person whose beneficial ownership of Common
Stock would be aggregated with such holder’s for the purposes of Section 13(d) of the Exchange Act, would beneficially own more
than the Beneficial Ownership Limitation. The Common Stock and the Warrants together may be deemed beneficially owned by Redmile as investment
manager of such private investment vehicles and/or sub-advised accounts. The reported securities may also be deemed beneficially owned
by Jeremy C. Green as the principal of Redmile. Redmile and Mr. Green each disclaim beneficial ownership of these shares, except to the
extent of its or his pecuniary interest in such shares, if any. |
|
** |
Percentage
based on (i) 12,823,696 shares of Common Stock outstanding as of December 18, 2023, as reported by the Issuer in its Form 8-K, plus (ii)
15,756 shares of Common Stock issuable upon exercise of certain of the Warrants, which due to the Beneficial Ownership Limitation is
the maximum number of shares that could be issued upon exercise of the Warrants. |
|
*** |
Percentage
based on 12,823,696 shares of Common Stock outstanding as of December 18, 2023, as reported by the Issuer in its Form 8-K. |
| Item 5. | Ownership of Five Percent or Less of a Class. |
If
this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner
of more than 5 percent of the class of securities, check the following ¨
| Item 6. | Ownership of More than Five Percent on Behalf of Another Person. |
N/A.
| Item 7. | Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company
or Control Person. |
See the response to Item 4.
| Item 8. | Identification and Classification of Members of the Group. |
N/A
| Item 9. | Notice of Dissolution of Group. |
N/A
By
signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held
for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and
are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in
connection with a nomination under § 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my
knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
Date: December 22, 2023
|
Redmile Group, LLC |
|
|
|
|
|
|
By: |
/s/ Jeremy C. Green |
|
|
Name: Jeremy C. Green
Title: Managing Member |
|
|
|
|
|
/s/ Jeremy C. Green |
|
|
Jeremy C. Green |
|
|
|
|
|
|
Redmile Biopharma Investments I, L.P.
By: Redmile Biopharma Investments I (GP), LLC, its general partner
By: Redmile Group, LLC, its managing member
|
|
By: |
/s/ Jeremy C. Green |
|
|
Name: Jeremy C. Green
Title: Managing Member |
Exhibit 99.1
Joint Filing Agreement
In accordance with Rule 13d-1(k)(1)
under the Securities Exchange Act of 1934, as amended (the “Exchange Act”), the undersigned hereby agree to the joint
filing on behalf of each of them of a Statement on Schedule 13G (including any and all amendments thereto, the “Schedule 13G”)
relating to the Common Stock, $0.000001 par value per share, of Neurogene Inc., which may be deemed necessary pursuant to Regulation 13D
or 13G promulgated under the Exchange Act.
The undersigned further agree
that each party hereto is responsible for the timely filing of the Schedule 13G, and for the accuracy and completeness of the information
concerning such party contained therein; provided, however, that no party is responsible for the accuracy or completeness of the information
concerning any other party, unless such party knows or has a reason to believe that such information is inaccurate.
It is understood and agreed
that a copy of this Joint Filing Agreement shall be attached as an exhibit to the Schedule 13G, filed on behalf of each of the parties
hereto.
IN WITNESS WHEREOF,
each of the undersigned has executed this Joint Filing Agreement as of the 22nd day of December, 2023.
|
Redmile Group, LLC |
|
|
|
|
|
/s/ Jeremy C. Green |
|
Name: Jeremy C. Green
Title: Managing Member |
|
|
|
|
/s/ Jeremy C. Green |
|
|
Jeremy C. Green |
|
|
|
|
|
|
Redmile Biopharma Investments
I, L.P.
By: Redmile Biopharma Investments I (GP), LLC, its general partner
By: Redmile Group, LLC, its managing member
|
|
By: |
/s/ Jeremy C. Green |
|
|
Name: Jeremy C. Green
Title: Managing Member |
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