FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Murphy-Chutorian Douglas
2. Issuer Name and Ticker or Trading Symbol

Semler Scientific, Inc. [ SMLR] ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__X__ Director                    __X__ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
Interim CEO
(Last)          (First)          (Middle)

C/O SEMLER SCIENTIFIC, INC., 2340-2348 WALSH AVENUE, SUITE 2344
3. Date of Earliest Transaction (MM/DD/YYYY)

5/16/2023
(Street)

SANTA CLARA, CA 95051
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)        (State)        (Zip)
Rule 10b5-1(c) Transaction Indication
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Common Stock Warrant (right to buy) $4.00 5/16/2023  D (1)    16875  6/7/2012 7/31/2023 Common Stock 16875 $25.74 0 I By Trust (2)
Common Stock Warrant (right to buy $4.50 5/16/2023  D (1)    60000  7/31/2013 7/31/2023 Common Stock 60000 $25.24 0 I By Trust (2)

Explanation of Responses:
(1) The Reporting Person sold these warrants to the Issuer. The net purchase price per warrant reflects the difference between the aggregate exercise price of the warrant and the aggregate fair market value of the shares underlying the warrant, based on the last trade price of the Issuer's common stock on May 16, 2023. The net sale dollar amount was $1,948,762.50 in total received from the Issuer.
(2) The warrants were held by the Murphy-Chutorian Family Trust U/D/T dated January 13, 1997, of which the Reporting Person is co-Trustee with his spouse.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Murphy-Chutorian Douglas
C/O SEMLER SCIENTIFIC, INC.
2340-2348 WALSH AVENUE, SUITE 2344
SANTA CLARA, CA 95051
XXInterim CEO

Signatures
/s/ Douglas Murphy-Chutorian, M.D.5/17/2023
**Signature of Reporting PersonDate


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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