FORM 5
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
[ ] Form 3 Holdings Reported
[ ] Form 4 Transactions Reported
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

ANNUAL STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

TRAVERSA SERGIO
2. Issuer Name and Ticker or Trading Symbol

RELMADA THERAPEUTICS, INC. [RLMD]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__X__ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
CEO
(Last)          (First)          (Middle)

C/O RELMADA THERAPEUTICS, INC.,  2222 PONCE DE LEON BLVD, 3RD FLOOR
3. Statement for Issuer's Fiscal Year Ended (MM/DD/YYYY)
12/31/2022 
(Street)

CORAL GABLES, FL 33134
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed(MM/DD/YYYY)
 
6. Individual or Joint/Group Filing(Check Applicable Line)

_X_ Form Filed by One Reporting Person
___ Form Filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date2A. Deemed Execution Date, if any3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Amount(A) or (D)Price

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date
(MM/DD/YYYY)
7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned at End of Issuer's Fiscal Year
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option (right to buy) $16.00 7/8/2021  G (1)  4131   (2)7/10/2022 Common Stock 4131 $0 0 D  
Stock Option (right to buy) $16.00 7/8/2021  G (1)  27123   (3)9/30/2023 Common Stock 27123 $0 6165 D  
Stock Option (right to buy) $54.00 7/8/2021  G (1)  8231   (4)2/23/2025 Common Stock 8231 $0 3019 D  
Stock Option (right to buy) $43.47 7/8/2021  G (1)  131250   (5)12/19/2029 Common Stock 131250 $0 218750 D  
Stock Option (right to buy) $33.43 7/8/2021  G (1)  93750   (6)1/7/2031 Common Stock 93750 $0 162500 D  
Stock Option (right to buy) $33.43 7/8/2021  G (1)  87500   (7)1/7/2031 Common Stock 87500 $0 162500 D  

Explanation of Responses:
(1) Represents a bona fide gift of stock options to a family trust. An independent trustee is trustee of the trust.
(2) The options were granted on July 10, 2012. 25% of the options vested upon the grant date and the remaining 75% of the options vested in equal quarterly increments over the next four (4) years, so that the last set of options vested in July 2016.
(3) The options were granted on September 30, 2013. 25% of the options vested upon the date of grant and the remaining 75% of the options vested in equal quarterly increments over the next four (4) years, so that the last set of options vested in September 2017.
(4) The options were granted on February 15, 2015. 6.25% of the options vested each quarter from the date of grant.
(5) The options were granted on December 19, 2019. 6.25% of the options vest each quarter from the date of grant.
(6) The options were granted on January 7, 2021. 6.25% of the options vest each quarter from the date of grant.
(7) The options were granted on January 7, 2021. 25% of the options vested one year from the grant date, and thereafter in equal quarterly increments of 6.25% over the following three years.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
TRAVERSA SERGIO
C/O RELMADA THERAPEUTICS, INC.
2222 PONCE DE LEON BLVD, 3RD FLOOR
CORAL GABLES, FL 33134
X
CEO

Signatures
/s/ Sergio Traversa2/2/2023
**Signature of Reporting PersonDate


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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